[Federal Register: May 20, 2004 (Volume 69, Number 98)]
[Notices]
[Page 29137]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr20my04-49]
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ENVIRONMENTAL PROTECTION AGENCY
[FRL-7665-5]
Peer Consultation Workshop on Physiologically-Based
Pharmacokinetic Modeling of Trichloroethylene and Its Metabolites
AGENCY: Environmental Protection Agency.
ACTION: Notice of a peer consultation workshop and public meeting.
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SUMMARY: The U.S. Air Force (USAF) and the U.S. Environmental
Protection Agency (EPA) are jointly announcing that Toxicology
Excellence for Risk Assessment (TERA), under contract to the USAF, will
convene a panel of experts and organize and conduct a peer consultation
workshop to discuss physiologically-based pharmacokinetic (PBPK)
modeling of trichloroethylene (TCE) and its metabolites. The public is
invited to attend this workshop.
DATES: The one-day peer consultation workshop will be held on June 29,
2004, from 8 a.m. to 4:30 p.m.
ADDRESSES: The peer consultation workshop will be held at Marriott
Kingsgate Conference Center at the University of Cincinnati,
Cincinnati, OH. TERA, under contract to the USAF, is organizing,
convening, and conducting the peer consultation workshop. To attend the
workshop as an observer, register by sending an e-mail to Patricia
Nance at nance@tera.org. If you wish to make comments available to
panel for consideration, please provide them to TERA before June 18,
2004. You can also call Patricia Nance at 513-542-7475 ext. 25, or send
a facsimile to 513-542-7487. The availability of the draft workgroup
document will be announced on the TERA Web site at http://www.tera.org/vera/TCEwelcome.htm
.
FOR FURTHER INFORMATION CONTACT: For more information on the workshop,
contact Dr. Jay Zhao, TERA; telephone: 513-542-7475 ext. 16; facsimile:
513-542-7487; or e-mail: zhao@tera.org. Additional information on this
joint USAF-EPA effort, including workshop information, registration,
and logistics, will be available on the TERA Web page at http://www.tera.org/vera/TCEwelcome.htm.
The USAF contact for this project is
Dr. Brian Howard; telephone: (210) 536-4548; facsimile: (210) 536-1130
or e-mail: Brian.Howard@brooks.af.mil. The EPA contact for this project
is Dr. Weihsueh Chiu; telephone: (202) 564-7789; facsimile: (202) 565-
0079; or e-mail: chiu.weihsueh@epa.gov.
SUPPLEMENTARY INFORMATION:
Background Information
The USAF and EPA are announcing a public peer consultation workshop
to discuss physiologically-based pharmacokinetic (PBPK) modeling of
trichloroethylene (TCE) and its metabolites. A joint USAF-EPA
workgroup, with support from TERA under contract to the USAF, has been
working to develop a harmonized PBPK model for TCE and its metabolites
based on the most recent science and data. The joint USAF-EPA
workgroup's efforts will be summarized in a draft document that will be
the basis of the peer consultation, and which will be made available to
the public several weeks before the workshop. The workgroup will
consider advice obtained from the peer consultation in revising and
calibrating its harmonized PBPK model, and in developing its final
report. The results of this joint USAF-EPA project will serve as
important input to ongoing TCE risk assessment activities, including a
planned multi-agency consultation with the National Academy of Sciences
on TCE science issues as well as EPA's revised TCE human health risk
assessment.
Dated: May 13, 2004.
Peter W. Preuss,
Director, National Center for Environmental Assessment.
[FR Doc. 04-11437 Filed 5-19-04; 8:45 am]
BILLING CODE 6560-50-P