[Federal Register: May 26, 2004 (Volume 69, Number 102)]
[Notices]
[Page 29953-29957]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr26my04-67]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
Study Effect of West Nile Virus Infection on Outcomes of
Pregnancy in Humans
Announcement Type: New.
Funding Opportunity Number: 04213.
Catalog of Federal Domestic Assistance Number: 93.283.
Key Dates:
Letter of Intent Deadline: June 15, 2004.
Application Deadline: July 6, 2004.
I. Funding Opportunity Description
Authority: This program is authorized under section 317(k)(2) of
the Public Health Service Act, (42 U.S.C. 247b(k)(2)), as amended.
Purpose and Research Objectives: The purpose of the program is to
determine whether West Nile Virus (WNV) infection of pregnant women has
adverse effects on the outcomes of pregnancy and to measure and
describe the effects, if any, on the health of children born to women
who were infected with WNV during their pregnancy.
This program addresses the ``Healthy People 2010'' focus area of
Immunization and Infectious Diseases.
Measurable outcomes of the program will be in alignment with the
following performance goal for the National Center on Birth Defects and
Developmental Disabilities: To improve the understanding and find the
causes and risk factors for birth defects and developmental
disabilities in order to develop prevention strategies.
WNV, a single-stranded RNA flavivirus with antigenic similarities
to Japanese encephalitis and St. Louis encephalitis viruses, is
transmitted to humans primarily through the bite of infected
mosquitoes. Flavivirus infection during pregnancy has been rarely
associated with both spontaneous abortion and neonatal illness, and
these viruses have not been known to cause birth defects in humans. In
2002, a 20-year old woman developed WNV encephalitis during the 27th
week of pregnancy. At 38 weeks of gestation she delivered a live infant
who appeared normal but on further examination had chorioretinitis and
cystic cerebral tissue destruction. Tests for cytomegalovirus, rubella
virus, herpes simplex virus, lymphocytic choriomeningitis virus,
enterovirus, and toxoplasma provided no evidence that any of these
agents had infected the infant. IgM antibody to WNV was found in cord
blood and in the infant's serum and cerebrospinal fluid, indicating
that the infant had acquired WNV infection in utero. WNV nucleic acid
was found in the placenta and umbilical cord tissue. Although it is not
possible to establish a direct link between WNV and the abnormalities
seen in this infant, the abnormalities observed are consistent with
those observed in intrauterine infections with other agents, suggesting
that they may be related to WNV intrauterine infection. Three other
instances of maternal WNV infection were investigated in 2002; in all
three instances the infants were born at full term with normal
appearance and without laboratory evidence of WNV infection, but
cranial imaging studies and ophthalmologic examinations were not
performed.
During 2002 a total of 4,156 cases of WNV illness in humans,
including 2,942 cases of neuroinvasive disease, were reported to the
Centers for Disease Control and Prevention (CDC) from state health
departments. During 2003 over 9,100 cases of WN illness, including over
2,600 cases of neuroinvasive disease were reported to CDC. CDC is
currently following over 70 women who were reported to have had WNV
disease during pregnancy in 2003.
The proportion of WNV infections during pregnancy that result in
congenital infection of the newborn is unknown. The spectrum of
clinical abnormalities associated with intrauterine infections with
other agents is wide and includes embryonic death and resorption,
abortion and stillbirth, prematurity, intrauterine growth retardation
and low birth weight, developmental anomalies and teratogenesis,
congenital disease, and persistent postnatal infection. The case
described above from 2002 suggests that intrauterine transmission of
WNV in some instances may have deleterious consequences, but the
spectrum of abnormalities and degree of risk of intrauterine
transmission are currently unknown. Improved understanding of these
issues is essential to allow appropriate counseling of women
[[Page 29954]]
exposed to WNV and to fully appreciate the impact of this emerging
infection.
In December of 2003, the Division of Vector-Borne Infectious
Diseases (DVBID) of the National Center for Infectious Diseases (NCID),
and the Division of Birth Defects and Developmental Disabilities
(DBDDD) of the National Center on Birth Defects and Developmental
Disabilities (NCBDDD) sought the opinion of experts on the evaluation
of congenital infections to develop interim guidelines for the
evaluation of infants born to mothers who were infected with WNV during
their pregnancy. These guidelines included careful evaluation of
physical characteristics, growth, development, and hearing for these
infants and ophthalmologic and dysmorphologic evaluations and imaging
of the brain for infants with evidence of congenitally acquired WNV
infection. Data obtained from these evaluations will need to be
collected and carefully reviewed in order to better understand the
effects of WNV on pregnancy and infant outcomes.
Activities: Recipient activities for this program are as follows:
(1) Develop a procedure for study subject enrollment. Collaborate
with staff at DVBID and DBDDD to enroll women who have been infected
with WNV during pregnancy into the study using the WNV pregnancy
registry maintained by DVBID as a primary source for enrollment.
Additional sources of enrollment may be used upon mutual agreement
between the recipient and CDC.
(2) Develop a procedure for enrollment of pregnant women who have
not been infected with WNV to serve as study controls.
(3) Develop a study protocol detailing the study design, sample
size calculations, study timeline, and provisions to maintain
confidentiality of study subjects.
(4) Ensure that all WNV-infected women enrolled in the study have
been or are reported to the state health department for the state in
which they reside.
(5) Evaluate outcomes of all pregnant women in the study to include
documentation of complications of pregnancy, miscarriage, premature
delivery and health of live-born infants according to the interim
guidelines published in the Morbidity and Mortality Weekly Report,
Volume 53, February 27, 2004, pages 154-157. Because of uncertainty
regarding diagnostic tests for congenital WNV infection; for purposes
of this project, all infants born to women who were suspected to be
infected with WNV during the first trimester of their pregnancy should
receive the evaluation recommended for infants suspected to have
congenital WNV infection, subject to consent of the parents. Infants
born to women suspected to have been infected with WNV during the
second or third trimester of pregnancy should be evaluated as indicated
in the interim guidelines mentioned above. More detailed evaluation may
be proposed by the recipient subject to ethical human research review
and approval of project staff at DVBID and DBDDD.
(6) Publish and disseminate program results.
CDC Responsibilities: In this cooperative agreement, CDC Scientists
(Scientific Liaisons) within the DBDDD/NCBDDD and the DVBID/NCID are an
equal partner with scientific and programmatic involvement during the
conduct of the project through technical assistance, advice, and
coordination. These Scientific Liaisons will:
(1) Participate in the development of the protocol.
(2) Participate in the analysis, interpretation, and reporting of
findings in the scientific literature and other media to the community
at large and the public policy community within the Federal government.
(3) Participate in data management, analysis of data, and
interpretation and dissemination of findings.
(4) Provide scientific consultation and technical assistance in the
design and conduct of the project, including protocol adherence,
outcome measures, and analytical approaches in participation with the
recipient organization.
CDC Scientific Program Administrator (SPA)
The CDC NCBDDD will appoint an SPA, apart from the NCBDDD and DVBID
Scientific Liaisons who will:
(1) Serve as the Program Official for the funded research
institutions.
(2) Carry out continuous review of all activities to ensure
objectives are being met.
(3) Attend Coordination Committee meetings for purposes of
assessing overall progress and for program evaluation purposes.
(4) Provide scientific consultation and technical assistance in the
conduct of the project as requested.
(5) Conduct site visits to recipient institutions to determine the
adequacy of the research and to monitor performance against approved
project objectives.
Collaborative Responsibilities
The planning and implementation of the cooperative aspects of the
study will be effected by a Coordination Committee consisting of the
Principal Investigator from the participating institution and the CDC
Scientific Liaisons. This Coordinating Committee will formulate a plan
for cooperative research.
At periodic coordination committee meetings, the group will: (1)
Make recommendations on the study protocol and data collection
approaches; (2) discuss the target populations that have been or will
be recruited; (3) identify and recommend solutions to unexpected study
problems; and (4) discuss ways to efficiently coordinate study
activities and best practices.
II. Award Information
Type of Award: Cooperative agreement. CDC involvement in this
program is listed in the Activities Section above.
Fiscal Year Funds: 2004.
Approximate Total Funding: $350,000.
Approximate Number of Awards: One.
Approximate Average Award: $350,000. (This amount is for the first
12-month budget period, and includes both direct and indirect costs.)
Floor of Award Range: None.
Ceiling of Award Range: $350,000 in initial budget period. If you
request a funding amount greater than the ceiling of the award range,
your application will be considered non-responsive, and will not be
entered into the review process. You will be notified that your
application did not meet the submission requirements. Based upon budget
constraints, requests for financial assistance are subject to reduction
in accordance with available resources.
Anticipated Award Date: September 1, 2004.
Budget Period Length: 12 months.
Project Period Length: Four years. Throughout the project period,
CDC's commitment to continuation of awards will be conditioned on the
availability of funds, evidence of satisfactory progress by the
recipient (as documented in required reports), and the determination
that continued funding is in the best interest of the Federal
government.
III. Eligibility Information
III.1. Eligible Applicants
Applications may be submitted by public and private non-profit
organizations and by governments and their agencies, such as:
Public non-profit organizations.
Private non-profit organizations.
Universities.
[[Page 29955]]
Colleges.
Research Institutions.
Hospitals.
State and local governments or their bona fide agents
(this includes the District of Columbia, the Commonwealth of Puerto
Rico, the Virgin Islands, the Commonwealth of the Northern Marianna
Islands, American Samoa, Guam, the Federated States of Micronesia, the
Republic of the Marshall Islands, and the Republic of Palau).
Political subdivisions of States (in consultation with
States).
A bona fide agent is an agency/organization identified by the State
as eligible to submit an application under the State eligibility in
lieu of a State application. If you are applying as a bona fide agent
of a State or local government, you must provide a letter from the
State as documentation of your status. Place this documentation behind
the first page of the application form.
III.2. Cost Sharing or Matching
Matching funds are not required for this program.
III.3. Other
Individuals Eligible to Become Principal Investigators: Any
individual with the skills, knowledge, and resources necessary to carry
out the proposed research is invited to work with their institution to
develop an application for support. Individuals from under-represented
racial and ethnic groups as well as individuals with disabilities are
always encouraged to apply for CDC programs.
Other Eligibility Requirements: If your application is incomplete
or non-responsive to the requirements listed below, it will not be
entered into the review process. You will be notified that your
application did not meet submission requirements.
Applicants must: (1) Document their present infrastructure,
capacity, expertise, and experience in conducting clinical and
epidemiological evaluations of birth defects and/or infectious diseases
with a national sample; and (2) have in the past shown their ability to
identify and enroll women with West Nile Virus or related birth defects
and/or infectious diseases in studies related to infections during
pregnancy and with related case controls.
Applicants must provide specific evidence to substantiate this
capacity, experience, and expertise. Through documentation of two pages
in length, applicants must provide specific evidence that they can
fully meet these eligibility criteria in order to be considered for
formal review. This information must be included as part of the
application and inserted immediately after the Face Page of the
application.
Note: Title 2 of the United States Code Section 1611 states that
an organization described in Section 501(c)(4) of the Internal
Revenue Code that engages in lobbying activities is not eligible to
receive Federal funds constituting an award, grant, or loan.
IV. Application and Submission Information
IV.1. Address To Request Application Package
To apply for this funding opportunity, use application form PHS 398
(OMB number 0925-0001 rev. 5/2001). Forms and instructions are
available in an interactive format on the CDC Web site, at the
following Internet address: http: //http://www.cdc.gov/od/pgo/forminfo.htm.
Forms and instructions are also available in an interactive format
on the National Institutes of Health (NIH) Web site at the following
Internet address: http://grants.nih.gov/grants/funding/phs398/phs398.html
.
If you do not have access to the Internet, or if you have
difficulty accessing the forms on-line, you may contact the CDC
Procurement and Grants Office Technical Information Management Section
(PGO-TIM) staff at: 770-488-2700. Application forms can be mailed to
you.
IV.2. Content and Form of Submission
Letter of Intent (LOI)
The LOI must be written in the following format:
Maximum number of pages: Two.
Font size: 12-point unreduced.
Paper size: 8.5 by 11 inches.
Page margin size: One-inch margins.
Printed only on one side of page.
Single spaced.
Written in plain language; avoid jargon.
The LOI must contain the following information: name, address, and
telephone number of the proposed Principal Investigator, number and
title of this program announcement, names of other key personnel,
designations of collaborating institutions and entities, and an outline
of the proposed work, recruitment approach, and expected outcomes.
Application: Follow the PHS 398 application instructions for
content and formatting of your application. For further assistance with
the PHS 398 application form, contact PGO-TIM staff at (770) 488-2700,
or contact GrantsInfo, telephone (301) 435-0714, e-mail:
GrantsInfo@nih.gov.
You must submit a signed original and five copies of your
application form. The PHS 398 grant application form requires the
applicant to enter the project title on page 1 (Form AA, ``Face Page'')
and the project description (abstract on page 2).
The main body of the application narrative should not exceed 30
single-spaced pages. This narrative research plan should address
activities to be conducted over the entire project period. Please note
that this maximum number of pages allowed exceeds the maximum number of
pages (25 pages) indicated in the PHS 398 grant application form
(``Research Grant Table of Contents'').
Additional information may be included in the application
appendices. The appendices will not be counted toward the narrative
page limit. This additional information may include curriculum vitae
and resumes for key project staff, organizational charts, letters of
support, etc.; and should be limited to those items relevant to the
requirements of this announcement.
All material must be typewritten, with 10 characters per inch type
(12 point) on 8\1/2\ by 11 inch white paper with one inch margins, no
headers or footers (except for applicant-produced forms such as
organizational charts, c. vitae, graphs and tables, etc). Applications
must be held together only by rubber bands or metal clips, and not
bound together in anyway (including attachments/appendices).
You are required to have a Dun and Bradstreet Data Universal
Numbering System (DUNS) number to apply for a grant or cooperative
agreement from the Federal government. Your DUNS number must be entered
on line 11 of the face page of the PHS 398 application form. The DUNS
number is a nine-digit identification number, which uniquely identifies
business entities. Obtaining a DUNS number is easy and there is no
charge. To obtain a DUNS number, access http://www.dunandbradstreet.com
or call 1-866-705-5711. For more information, see the CDC Web site at:
http://www.cdc.gov/od/pgo/funding/pubcommt.htm.
Additional requirements that may require you to submit additional
documentation with your application are listed in section ``VI.2.
Administrative and National Policy Requirements.''
IV.3. Submission Dates and Time
Letter of Intent (LOI) Deadline Date: June 15, 2004.
CDC requests that you send a LOI if you intend to apply for this
program.
[[Page 29956]]
Although the LOI is not required, not binding, and does not enter into
the review of your subsequent application, the LOI will be used to
gauge the level of interest in this program, and will allow CDC to plan
the application review.
Application Deadline Date: July 6, 2004.
Explanation of Deadlines: Applications must be received in the CDC
Procurement and Grants Office by 4 p.m. eastern time on the deadline
date. If you send your application by the United States Postal Service
or commercial delivery service, you must ensure that the carrier will
be able to guarantee delivery of the application by the closing date
and time. If CDC receives your application after closing due to: (1)
Carrier error, when the carrier accepted the package with a guarantee
for delivery by the closing date and time, or (2) significant weather
delays or natural disasters, you will be given the opportunity to
submit documentation of the carrier's guarantee. If the documentation
verifies a carrier problem, CDC will consider the application as having
been received by the deadline.
This announcement is the definitive guide on application submission
address and deadline. It supersedes information provided in the
application instructions. If your application does not meet the
deadline above, it will not be eligible for review, and will be
discarded. You will be notified that your application did not meet the
submission requirements.
CDC will not notify you upon receipt of your application. If you
have a question about the receipt of your application, first contact
your courier. If you still have a question, contact the PGO-TIM staff
at: 770-488-2700. Before calling, please wait three days after the
application deadline. This will allow time for applications to be
processed and logged.
IV.4. Intergovernmental Review of Applications
Executive Order 12372 does not apply to this program.
IV.5. Funding Restrictions
Restrictions, which must be taken into account while writing your
budget are that project funds cannot be used to supplant other
available applicant or collaborating agency funds for construction or
for lease or purchase of facilities or space.
If you are requesting indirect costs in your budget, you must
include a copy of your indirect cost rate agreement. If your indirect
cost rate is a provisional rate, the agreement must be less than 12
months from the application due date.
IV.6. Other Submission Requirements
LOI Submission Address
Lisa T. Garbarino, Public Health Analyst, National Center on Birth
Defects and Developmental Disabilities, CDC, 1600 Clifton Road,
Mailstop E-87, Atlanta, Georgia 30333. E-mail address: lgt1@cdc.gov.
Application Submission Address: Submit the original and five copies
of your application by mail or express delivery service to: Technical
Information Management--PA, CDC Procurement and Grants Office, 2920
Brandywine Road, Atlanta, Georgia 30341.
Applications may not be submitted by fax or e-mail at this time.
V. Application Review Information
V.1. Review Criteria
You are required to provide measures of outcome and effectiveness
that will demonstrate the accomplishment of the various identified
objectives of the cooperative agreement. Measures of effectiveness must
relate to the performance goals stated in the ``Purpose'' section of
this announcement. Measures must be objective and quantitative, and
must measure the intended outcome. These measures of effectiveness must
be submitted with the application and will be an element of evaluation.
The goals of CDC-supported research are to advance the
understanding of biological systems, improve the control and prevention
of disease and injury, and enhance health. In the written comments,
reviewers will be asked to evaluate the application in order to judge
the likelihood that the proposed research will have a substantial
impact on the pursuit of these goals. The scientific review group will
address the application's overall score, weighting them as appropriate
for each application. The application does not need to be strong in all
categories to be judged likely to have major scientific impact and thus
deserve a high priority score.
Under the evaluation criteria noted below, applicants must describe
how they will address the program components as they relate to the
Purpose and Research Objectives, and Recipient Activities as cited in
this Announcement.
Your application will be evaluated against the following criteria:
1. Background/Understanding/Competency, including:
a. Identification of the problem and justification for the study,
including accounts of understanding of West Nile Virus and its
association with human illness, morbidity, and mortality;
b. Accounts as to the level of review of relevant literature
undertaken and the discussion of the foundation in science being
utilized in addressing the purpose of the research;
c. Description of the understanding of the implications and
interrelationships between the vector and human host responses;
d. Accounts of the applicants understanding of the possible
association between West Nile Virus infection and outcomes of pregnancy
in humans;
e. Discussion of the unique capabilities residing in the applicant
organization in conducting clinical and epidemiological evaluations of
birth defects and/or infectious diseases on a national basis;
f. Description of the study goals, objectives and/or hypotheses,
and
g. Intended use and applicability of study findings.
2. Research Approach and Organizational Capacity, including:
a. The overall strength and feasibility of the research design with
an emphasis on pregnant women and the health of children born to women
who were infected with West Nile Virus during pregnancy;
b. Presentation of how the applicant is fully able to identify and
enroll women with West Nile Virus during pregnancy and related case
controls;
c. Description and justification of the study population, including
case definitions, number of participants, selection criteria, and
methods for recruiting, enrolling, and sustaining participation;
d. Description of the consent process, including procedures for
informing participants about the study and methods for obtaining
consent;
e. The detailed description of the research design and all follow-
up protocols, including access to a national sample;
f. Description of all study instruments including survey
questionnaires, and a discussion of their reliability and validity;
g. Data handling and analysis plans, including statistical
methodology, data entry, storage, and disposition; and
h. Plans for disseminating and reporting results to multiple (and
applicant-identified) target audiences.
3. Investigators/Collaborators/and Management Plans, including:
a. Description of the major collaborators and their explicit
contributions to project objectives;
[[Page 29957]]
b. Discussion of investigator(s) qualifications, roles, tasks, time
commitments, and responsibilities; and
c. Detailed work plan with specific time frames for implementation
of the project. This includes the presentation of overarching goals for
the full four-year project period with a detailed work plan outlining
monthly or quarterly objectives covering the first two budget years.
4. Evaluation Plan, including:
a. Description of how progress will be monitored and evaluated over
the entire course of the research;
b. The extent to which project goals are to be attained and
specific objectives accomplished; and
c. Description of expected outcomes and how the overall
effectiveness of the research will be determined.
5. Budget Description and Justification: This includes the
comprehensiveness and adequacy of the proposed budget in relation to
program operations, collaborations, and services; and the extent to
which the budget is reasonable, clearly justified, accurate, and
consistent with the purposes of this research.
6. Protections: Does the application adequately address the
requirements of title 45 CFR part 46 for the protection of human
subjects? This criteria will not be scored; however, an application can
be disapproved if the research risks are sufficiently serious and
protection against risks is so inadequate as to make the entire
application unacceptable.
7. Inclusion: Does the application adequately address the CDC
policy requirements regarding the inclusion of women, ethnic, and
racial groups in the proposed research? This includes:
a. The proposed plan for the inclusion of both sexes and racial and
ethnic minority populations for appropriate representation.
b.The proposed justification when representation is limited or
absent.
c. A statement as to whether the design of the study is adequate to
measure differences when warranted.
d. A statement as to whether the plans for recruitment and outreach
for study participants include the process of establishing partnerships
with community(ies) and recognition of mutual benefits.
V.2. Application Review Process
Applications will be reviewed by CDC staff for completeness by the
Procurement and Grants Office (PGO) and for responsiveness by NCBDDD as
outlined in the ``Other Eligibility Requirements''. Incomplete
applications and applications that are non-responsive will not advance
through the review process. Applicants will be notified that their
application did not meet submission requirements and will not receive
further consideration.
Applications, which are complete and responsive, will be subject to
a preliminary evaluation (triage) by the scientific review group
(Special Emphasis Panel--SEP) to determine if the application is of
sufficient technical and scientific merit to warrant further review by
the SEP.
Applications that are determined to be non-competitive will not be
considered, and the SEP will notify the investigator/program director
and the official signing for the applicant organization. A dual review
process will then evaluate those applications determined to be
competitive.
V.3. Anticipated Award Date
September 1, 2004.
VI. Award Administration Information
VI.1. Award Notices
If your application is to be funded, you will receive a Notice of
Grant Award (NGA) from the CDC Procurement and Grants Office. The NGA
shall be the only binding, authorizing document between the recipient
and CDC. The NGA will be signed by an authorized Grants Management
Officer, and mailed to the recipient fiscal officer identified in the
application. Unsuccessful applicants will receive notification of the
results of the application review by mail.
VI.2. Administrative and National Policy Requirements
45 CFR Parts 74 and 92
For more information on the Code of Federal Regulations, see the
National Archives and Records Administration at the following Internet
address: http://www.access.gpo.gov/nara/cfr/cfr-table-search.html.
The following additional requirements apply to this project:
AR-1 Human Subjects Requirements.
AR-2 Requirement for Inclusion of Women and Racial and
Ethnic Minorities in Research.
AR-9 Paperwork Reduction Act Requirements.
AR-10 Smoke-Free Workplace Requirements.
AR-11 Healthy People 2010.
AR-12 Lobbying Restrictions.
AR-14 Accounting Systems Requirements.
AR-15 Proof of Non-Profit Status.
AR-22 Research Integrity.
AR-25 Release and Sharing of Data.
Additional information on these requirements can be found on the
CDC Web site at the following Internet address: http://www.cdc.gov/od/pgo/funding/ARs.htm
.
VI.3. Reporting
You must provide CDC with an original, plus two copies of the
following reports:
1. Interim progress report, (PHS 2590, OMB Number 0925-0001, rev.
5/2001), on a date to be determined for your project for each
subsequent budget year. The progress report will serve as your non-
competing continuation application, and must contain the following
elements:
a. Current Budget Period Activities and Objectives.
b. Current Budget Period Financial Progress.
c. New Budget Period Program Proposed Activities and Objectives.
d. Budget.
e. Additional Requested Information.
f. Measures of Effectiveness.
2. Financial status report and annual report, no more than 90 days
after the end of the budget period.
3. Final financial and performance reports, no more than 90 days
after the end of the project period.
These reports must be sent to the Grants Management Specialist
listed in the ``Agency Contacts'' section of this announcement.
VII. Agency Contacts
For general questions about this announcement, contact: Technical
Information Management Section (PGO-TIM), CDC Procurement and Grants
Office, 2920 Brandywine Road, Atlanta, Georgia 30341. Telephone: 770-
488-2700.
For program technical assistance, contact: Lisa T. Garbarino,
Public Health Analyst, National Center on Birth Defects and
Developmental Disabilities, CDC, 1600 Clifton Road, Mailstop E-87,
Atlanta, Georgia 30333. E-mail address: lgt1@cdc.gov; telephone: 404-
498-3979.
For financial, grant management, or budget assistance, contact:
Sylvia Dawson, Grants Management Specialist, CDC Procurement and Grants
Office, 2920 Brandywine Road, Atlanta, Georgia 30341. Telephone: 770-
488-2771; e-mail: snd8@cdc.gov.
Dated: May 20, 2004.
William P. Nichols,
Acting Director, Procurement and Grants Office, Centers for Disease
Control and Prevention.
[FR Doc. 04-11872 Filed 5-25-04; 8:45 am]
BILLING CODE 4163-18-P