[Federal Register: July 6, 2005 (Volume 70, Number 128)]
[Notices]               
[Page 38938-38939]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr06jy05-114]                         

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DEPARTMENT OF HEALTH AND HUMAN SERVICES

Centers for Disease Control and Prevention

[60 Day-05-0010]

 
Proposed Data Collections Submitted for Public Comment and 
Recommendations

    In compliance with the requirement of section 3506(c)(2)(A) of the 
Paperwork Reduction Act of 1995 for opportunity for public comment on 
proposed data collection projects, the Centers for Disease Control and 
Prevention (CDC) will publish periodic summaries of proposed projects. 
To request more information on the proposed projects or to obtain a 
copy of the data collection plans and instruments, call 404-371-5983 
and send comments to Seleda Perryman, CDC Assistant Reports Clearance 
Officer, 1600 Clifton Road, MS-D74, Atlanta, GA 30333 or send an e-mail 
to omb@cdc.gov.
    Comments are invited on: (a) Whether the proposed collection of 
information is necessary for the proper performance of the functions of 
the agency, including whether the information shall have practical 
utility; (b) the accuracy of the agency's estimate of the burden of the 
proposed collection of information; (c) ways to enhance the quality, 
utility, and clarity of the information to be collected; and (d) ways 
to minimize the burden of the collection of information on respondents, 
including through the use of automated collection techniques or other 
forms of information technology. Written comments should be received 
within 60 days of this notice.

Proposed Project

    The National Birth Defects Prevention Study (OMB 0920-0010)--
Extension--The Division of Birth Defects and Developmental Disabilities 
(DBDDD), National Center on Birth Defects and Developmental 
Disabilities (NCBDDD), Centers for Disease Control and Prevention 
(CDC).

Background and Brief Description

    CDC has been monitoring the occurrence of serious birth defects and 
genetic diseases in Atlanta since 1967 through the Metropolitan Atlanta 
Congenital Defects Program (MACDP). The MACDP is a population-based 
surveillance system for birth defects in the 5 counties of Metropolitan 
Atlanta. Its primary purpose is to describe the spatial and temporal 
patterns of birth defects occurrence and serve as an early warning 
system for new teratogens. From 1993 to 1996, the Division of Birth 
Defects and Developmental Disabilities (DBDDD) conducted the Birth 
Defects Risk Factor Surveillance (BDRFS) study, a case-control study of 
risk factors for selected birth defects. Infants with birth defects 
were identified through MACDP and maternal interviews and clinical/
laboratory tests were conducted on approximately 300 cases and 100 
controls per year. Controls were selected from among normal births in 
the same population. In 1997 the BDRFS became the National Birth 
Defects Prevention Study (NBDPS). The major components of the study did 
not change.
    The NBDPS is a case-control study of major birth defects that 
includes cases identified from existing birth defect

[[Page 38939]]

surveillance registries in ten states (including metropolitan Atlanta). 
Control infants are randomly selected from birth certificates or birth 
hospital records. Mothers of case and control infants are interviewed 
using a computer-assisted telephone interview. Parents are asked to 
collect cheek cells from themselves and their infants for DNA testing. 
Information gathered from both the interviews and the DNA specimens 
will be used to study independent genetic and environmental factors as 
well as gene-environment interactions for a broad range of carefully 
classified birth defects.
    This request is submitted to obtain OMB clearance for three 
additional years. There is no cost to respondents other than their 
time.

                                       Estimate of Annualized Burden Hours
----------------------------------------------------------------------------------------------------------------
                                                                                  Average burden/
                 Type of burden                      Number of     Frequency of    response  (in   Annual burden
                                                    respondents      response         hours)        (in hours)
----------------------------------------------------------------------------------------------------------------
NBDPS case/control interview....................             400               1               1             400
Biologic specimen collection....................           1,200               1           10/60             200
                                                 -----------------
    Total.......................................  ..............  ..............  ..............             600
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    Dated: June 21, 2005.
Joan F. Karr,
Acting Reports Clearance Officer, Centers for Disease Control and 
Prevention.
[FR Doc. 05-13246 Filed 7-5-05; 8:45 am]

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