[Federal Register: August 24, 2005 (Volume 70, Number 163)]
[Notices]
[Page 49622-49623]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr24au05-68]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[30Day-05-03AA]
Proposed Data Collections Submitted for Public Comment and
Recommendations
The Centers for Disease Control and Prevention (CDC) publishes a
list of information collection requests under review by the Office of
Management and Budget (OMB) in compliance with the Paperwork Reduction
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call
the CDC Reports Clearance Officer at (404) 371-5983 or send an e-mail
to omb@cdc.gov. Send written comments to CDC Desk Officer, Human
Resources and Housing Branch, New Executive Office Building, Room
10235, Washington, DC 20503 or by fax to (202) 395-6974. Written
comments should be received within 30 days of this notice.
Proposed Project
Potential Reproductive and Neurological Effects of Exposure to
Acrylamide--NEW--The National Institute for Occupational Safety and
Health (NIOSH), Centers for Disease Control and Prevention (CDC).
The mission of the National Institute for Occupational Safety and
Health (NIOSH) is to promote safety and health at work for all people
through research and prevention. Consistent with this mission, NIOSH is
undertaking a study of the reproductive and neurobehavioral effects of
occupational exposure to acrylamide. Male acrylamide workers and
control workers (N = 100 per group) will be recruited from
manufacturing, end-user, and non-exposed settings. Exposure will be
characterized by acrylamide hemoglobin, adduct and urinary metabolite
levels, ambient area, personal air, and dermal sampling. Reproductive
effects will be evaluated by examining semen quality, sperm DNA
integrity, reproductive hormone levels, and prostate specific antigen
(PSA) levels.
Neurobehavioral effects will be assessed using sensation-tactile,
postural stability, grooved pegboard, and simple reaction time tests.
Two questionnaires will be administered on one occasion. Questionnaire
information will be collected concurrently to augment test
interpretation, adjust for potential confounders and covariates during
regression analysis, correlate specific jobs and job activities with
exposure measurements, and for validation purposes. Findings from this
study will clarify if the adverse reproductive effects observed in
animal studies are also present in acrylamide-exposed male workers, and
if preclinical neurobehavioral deficits are present at acrylamide doses
currently considered to be within safe limits. This study is scheduled
for implementation between 2005 and 2007. There is no cost to the
respondent other than their time for participating. The annualized
estimated burden for this data collection is 54 hours.
Estimate of Annualized Burden Table
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Average
Number of Number of burden/
Survey questionnaires respondents responses/ response
respondent (hours)
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Medical & Reproductive History Questionnaire.................... 67 1 13/60
Occupational History Questionnaire.............................. 67 1 34/60
Non-participant Questionnaire................................... 17 1 2/60
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[[Page 49623]]
Dated: August 11, 2005.
Joan F. Karr,
Acting Reports Clearance Officer, Centers for Disease Control and
Prevention.
[FR Doc. 05-16367 Filed 8-23-05; 8:45 am]
BILLING CODE 4163-18-P