[Federal Register: September 21, 2005 (Volume 70, Number 182)]
[Notices]
[Page 55399-55400]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr21se05-84]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[30 Day-05-04OP]
Proposed Data Collections Submitted for Public Comment and
Recommendations
The Centers for Disease Control and Prevention (CDC) publishes a
list of information collection requests under review by the Office of
Management and Budget (OMB) in compliance with the Paperwork Reduction
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call
the CDC Reports Clearance Officer at (404) 371-5983. Send written
comments to CDC, Desk Officer, Human Resources and Housing Branch by
fax to (202) 395-6974. Written comments should be received within 30
days of this notice.
Proposed Project
Delayed Symptoms Associated with the Convalescent Period of a
Dengue Infection--New--National Center for Infectious Diseases (NCID),
Centers for Disease Control and Prevention (CDC).
Background and Brief Description
Dengue is a vector-borne febrile disease of the tropics transmitted
most often by the mosquito Aedes aegypti. Symptoms of the acute disease
include fever, headache, rash, retro-orbital pain, myalgias,
arthralgias, vomiting, abdominal pain and hemorrhagic manifestations.
A number of symptoms are mentioned in the medical literature as
associated with the convalescent period after dengue infection,
including depression, dementia, loss of sensation, paralysis of lower
and upper extremities and larynx, epilepsy, tremors, manic psychosis,
amnesia, loss of visual acuity, hair loss, and peeling of skin. The
evidence for these findings has derived mainly from case series and
case reports, but no analytic study has been conducted to define the
timing, frequency, and severity of these symptoms, and quantity the
magnitude of the association between dengue infection and each of these
disorders.
The objective of this study is to compare mental health disorders
and other delayed complications associated with dengue infection and
convalescence among study groups. The study will be conducted in Puerto
Rico, where dengue is endemic, in collaboration with Dengue Branch of
the Centers for Disease Control and Prevention. Laboratory positive
confirmed cases of dengue, laboratory negative suspected dengue cases,
and neighborhood controls will be prospectively enrolled in the study.
Telephone interviews will be conducted and information will be
collected prospectively regarding symptoms experienced during the first
five months after the onset of symptoms of a dengue infections. There
are no costs to the respondents other than their time. The estimated
annualized burden is 426 hours.
Estimated Total Annualized Burden Hours
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Number of Average burden
Respondents Number of responses per per response
respondents respondent (in hrs.)
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Screeners.................................................... 810 2 1/60
Laboratory positive confirmed dengue......................... 200 2 20/60
Dengue negative control...................................... 200 2 20/60
Neighborhood control......................................... 200 2 20/60
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[[Page 55400]]
Joan Karr,
Acting Reports Clearance Officer, Centers for Disease Control and
Prevention.
[FR Doc. 05-18786 Filed 9-20-05; 8:45 am]
BILLING CODE 4163-18-P