[Federal Register: October 5, 2006 (Volume 71, Number 193)]
[Notices]
[Page 58865-58866]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr05oc06-61]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[60 Day-06-0425X]
Proposed Data Collections Submitted for Public Comment and
Recommendations
In compliance with the requirement of Section 3506(c)(2)(A) of the
Paperwork Reduction Act of 1995 for opportunity for public comment on
proposed data collection projects, the Centers for Disease Control and
Prevention (CDC) will publish periodic summaries of proposed projects.
To request more information on the proposed projects or to obtain a
copy of the data collection plans and instruments, call 404-639-5960
and send comments to Seleda Perryman, CDC Assistant Reports Clearance
Officer, 1600 Clifton Road, MS-D74, Atlanta, GA 30333 or send an e-mail
to omb@cdc.gov.
Comments are invited on: (a) Whether the proposed collection of
information is necessary for the proper performance of the functions of
the agency, including whether the information shall have practical
utility; (b) the accuracy of the agency's estimate of the burden of the
proposed collection of information; (c) ways to enhance the quality,
utility, and clarity of the information to be collected; and (d) ways
to minimize the burden of the collection of information on respondents,
including through the use of automated collection techniques or other
forms of information technology. Written comments should be received
within 60 days of this notice.
Proposed Project
The National Centers for Autism and Developmental Disabilities
Research and Epidemiology (CADDRE) Study--New--National Center on Birth
Defects and Developmental Disabilities (NCBDDD), Centers for Disease
Control and Prevention (CDC).
Background and Brief Description
The Children's Health Act of 2000 mandated CDC to establish autism
surveillance and research programs to address the number, incidence,
correlates, and causes of autism and related disabilities. Under the
provisions of this act, CDC funded 5 CADDRE centers including the
California Department of Health and Human Services, Colorado Department
of Public Health and Environment, Johns Hopkins University, the
University of Pennsylvania, and the University of North Carolina at
Chapel Hill. CDC National Center on Birth Defects and Developmental
Disabilities will participate as the 6th site. The multi-site,
collaborative study will be an epidemiological investigation of
possible causes for the autism spectrum disorders.
Study participants will be selected from children born in and
residing in the following six areas: Atlanta metropolitan area, San
Francisco Bay area, Denver metropolitan area, Baltimore metropolitan
area, Philadelphia metropolitan area, and Central North Carolina.
Children with autism spectrum disorders will be compared to children
with other developmental problems, referred to as the
neurodevelopmentally impaired group (NIC), as well as children who do
not have developmental problems, referred to as the subcohort.
Data collection methods will consist of the following: (1) Medical
record review of the child participant; (2) medical record review of
the biological mother of the child participant; (3) a packet sent to
the participants with self-administered questionnaires and a buccal
swab kit; (4) a telephone interview focusing on pregnancy-related
events and early life history (biological mother and/or primary
caregiver interview); (5) a child development evaluation (more
comprehensive for case participants than for the control group
participants); (6) parent-child development interview (for case
participants only) administered over the telephone or in-person; (7) a
physical exam of the child participant; (8) biological sampling of the
child participant (blood and hair); and (9) biological sampling of the
biological parents of the child participant (blood only). There is no
cost to respondents other than their time.
Estimated Annualized Burden Hours
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Number of Avg. burden per
Form Number of responses per response (in Total burden
respondents respondent hours) hours
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1. Initial Contact by Mail.............. 17,610 1 0.17 2,994
2. Invitation Telephone Contact......... 8,922 1 0.33 2,944
3. Self-administered Questionnaires and 3,456 1 3.17 10,955
buccal sample..........................
4. Caregiver Interview by telephone..... 3,282 1 0.83 2,724
5. Child Clinic Visit (Child Development 3,114
Evaluation, physical exam, and
biosamples)............................
Case................................ 810 1 2.0 1,620
NIC................................. 1,170 1 1.33 1,556
Subcohort........................... 1,134 1 1.33 1,508
6. Parent-Child Development Interview 810 1 3.17 2,568
(Case participants only)...............
7. Parent biosamples.................... 3,114 1 0.25 779
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Total........................... ................ ................ ................ 27,648
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[[Page 58866]]
Dated: September 29, 2006.
Joan F. Karr,
Acting Reports Clearance Officer, Centers for Disease Control and
Prevention.
[FR Doc. E6-16455 Filed 10-4-06; 8:45 am]
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