[Federal Register: November 14, 2006 (Volume 71, Number 219)]
[Notices]
[Page 66331-66332]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr14no06-40]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[30Day-07-06AW]
Agency Forms Undergoing Paperwork Reduction Act Review
The Centers for Disease Control and Prevention (CDC) publishes a
list of information collection requests under review by the Office of
Management and Budget (OMB) in compliance with the Paperwork Reduction
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call
the CDC Reports Clearance Officer at (404) 639-5960 or send an e-mail
to omb@cdc.gov. Send written comments to CDC Desk Officer, Office of
Management and Budget, Washington, DC or by fax to (202) 395-6974.
Written comments should be received within 30 days of this notice.
Proposed Project
Supplement to the National Birth Defects Prevention Study:
Qualitative Assessment of the Attitudes Mothers Have Toward Collecting
Biological Specimens on their Infants and Young Children to Study Risk
Factors for Birth Defects and Preterm Delivery--New--National Center on
Birth Defects and Developmental Disabilities (NCBDDD), Centers for
Disease Control and Prevention (CDC).
Background and Brief Description
The National Center on Birth Defects and Developmental Disabilities
(NCBDDD), Centers for Disease Control and Prevention (CDC), has been
conducting the National Birth Defects Prevention Study (OMB number
0920-0010, Exp. 5/31/2009) since 1997. The NBDPS is a case-control
study of major birth defects that includes cases identified from
existing birth defect surveillance registries in nine states, including
metropolitan Atlanta. Control infants are randomly selected from birth
certificates or birth hospital records. Mothers of case and control
infants are interviewed using a computer-assisted telephone interview.
Parents are asked to collect cheek cells from themselves and their
infants for DNA testing. Information gathered from both the interviews
and the DNA specimens will be used to study independent genetic and
environmental factors as well as gene-environment interactions for a
broad range of carefully classified birth defects.
This proposed supplement to the National Birth Defects Prevention
Study will use qualitative research to provide data on the barriers to
participation in the collection of biological specimens by mothers on
themselves, their infants, and young children. It is costly to
implement the collection of biological specimens into an interview/
questionnaire-based study. However, an ever-increasing number of
studies include the examination of environmental and genetic
interactions to help medical and public health professionals' better
target appropriate interventions. A critical component for studies of
gene variants is the collection of biological specimens. Participation
and non-participation in the collection of biological specimens is not
fully understood. We will conduct multiple well-designed focus groups
to assess the attitudes of both mothers who participated and mothers
who did not participate in the collection of biological specimens to
increase the effectiveness of these studies. This information will be
useful to many groups at the CDC who are currently collecting
biological specimens from infants and their families but with less than
optimal response rates and those who are working to implement studies
that include the use of biological specimens.
Scientists from the National Birth Defects Prevention Study (NBDPS)
in NCBDDD, the Pregnancy Risk Assessment Monitoring System (PRAMS) in
NCCDPHP, and the Office of Genomics and Disease Prevention (OGDP) have
received Collaborative Initiative intramural funding to conduct focus
groups aimed at gaining insight into the barriers and motivations women
have for participating in the collection of biological specimens. Among
the three collaborating Centers within the Coordinating Center for
Health Promotion, NCBDDD's National Birth Defects Prevention Study
provides a unique opportunity for exploring the barriers and
motivations toward collection of genetic material. This focus group
project will recruit mothers who participated in the maternal interview
for the National Birth Defects Prevention Study (NBDPS). There are no
costs to the respondents other than their time. The total estimated
annualized burden hours are 214.
[[Page 66332]]
Estimated Annualized Burden Hours
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Avg. burden/
Type of respondent Number of Frequency of response (in Annual burden
respondents response hours) (in hours)
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Focus group Participants........................ 72 1 2.5 180
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Dated: November 6, 2006.
Joan F. Karr,
Acting Reports Clearance Officer, Centers for Disease Control and
Prevention.
[FR Doc. E6-19144 Filed 11-13-06; 8:45 am]
BILLING CODE 4163-18-P