[Federal Register Volume 72, Number 246 (Wednesday, December 26, 2007)]
[Notices]
[Pages 73021-73022]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: E7-24929]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[30 Day-08-07AW]
Agency Forms Undergoing Paperwork Reduction Act Review
The Centers for Disease Control and Prevention (CDC) publishes a
list of information collection requests under review by the Office of
Management and Budget (OMB) in compliance with the Paperwork Reduction
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call
the CDC Reports Clearance Officer at (404) 639-5960 or send an e-mail
to [email protected]. Send written comments to CDC Desk Officer, Office of
Management and Budget, Washington, DC or by fax to (202) 395-6974.
Written comments should be received within 30 days of this notice.
Proposed Project
Experimental and Theoretical Study of Early Detection and Isolation
of Influenza--New--The National Institute for Occupational Safety and
Health (NIOSH), Centers for Disease Control and Prevention (CDC).
Background and Brief Description
The Federal Occupational Safety and Health Act of 1970, section
501, enables NIOSH to carry out research relevant to the health and
safety of workers. Some diseases like influenza and Severe Acute
Respiratory Syndrome (SARS) can be spread when people produce clouds of
droplets (called aerosols) by coughing or sneezing. Aerosol
transmission of infectious diseases is of particular interest today
because of increased concern over a possible global influenza pandemic.
The possible airborne spread of influenza is especially important to
health-care workers and emergency responders, who face a much greater
risk of exposure than does the general public. However, substantial
gaps exist in our understanding of the generation and spread of
infectious aerosols containing influenza. This lack of information
hampers the ability of health scientists to model and predict the
transmission of influenza by airborne particles and to understand
whether or not aerosols are likely to be an important route of
transmission of influenza during a pandemic.
The purpose of this study is to gain a better understanding of the
production and dissemination of aerosols containing the influenza
virus. The results of this research will give
[[Page 73022]]
scientists and health professionals greater insight into the airborne
transmission of influenza and allow them to better assess the potential
effectiveness of preventive measures.
The first part of this study will measure the quantity and size
distribution of aerosol droplets produced by people with influenza when
they cough. To accomplish this, volunteers with influenza-like illness
will be asked to provide an oral swab for influenza testing, and then
will cough into a spirometer. The aerosol produced by each person will
be measured using commercially-available instrumentation. The oral
swabs will be processed after the aerosol experiments are completed.
The second part of this study will determine the amount and size of
airborne particles containing influenza virus that are present in a
hospital emergency department during influenza season. Health care
workers will be recruited to wear small aerosol collection devices as
they go about their normal duties. The collected samples will then be
analyzed for influenza virus. Adult patients in the emergency
department with influenza-like illness will be asked to provide an oral
swab to test for the flu virus in order to estimate the number of
potential sources of viral-laden airborne particles. There will be no
costs to study participants. The total estimated annualized burden
hours are 35.
Total Estimated Annualized Burden Table
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Number of Average
Number of responses burden per
Type of respondent Form respondents per response
respondent (in hours)
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Specific Aim 1: Volunteers with influenza
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Initial participants...................... Health questionnaire......... 42 1 5/60
Qualified participants.................... Consent form................. 40 1 20/60
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Specific Aim 2: Health care workers
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Initial participants...................... Health questionnaire......... 32 1 5/60
Qualified participants.................... Consent form................. 30 1 20/60
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Specific Aim 2: Emergency Department patients
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Participants.............................. Consent form................. 15 1 20/60
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Dated: December 14, 2007.
Maryam I. Daneshvar,
Acting Reports Clearance Officer, Centers for Disease Control and
Prevention.
[FR Doc. E7-24929 Filed 12-21-07; 8:45 am]
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