[Federal Register: April 9, 2007 (Volume 72, Number 67)]
[Notices]
[Page 17553-17554]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr09ap07-77]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Centers for Disease Control and Prevention
[30Day-07-06AX]
Agency Forms Undergoing Paperwork Reduction Act Review
The Centers for Disease Control and Prevention (CDC) publishes a
list of information collection requests under review by the Office of
Management and Budget (OMB) in compliance with the Paperwork Reduction
Act (44 U.S.C. Chapter 35). To request a copy of these requests, call
the CDC Reports Clearance Officer at (404) 639-5960 or send an e-mail
to omb@cdc.gov. Send written comments to CDC Desk Officer, Office of
Management and Budget, Washington, DC or by fax to (202) 395-6974.
Written comments should be received within 30 days of this notice.
Proposed Project
Risk Perception, Worry, and Use of Ovarian Cancer Screening Among
Women At High, Elevated, and Average Risk of Ovarian Cancer--NEW--
National Center for Chronic Disease Prevention and Health Promotion
(NCCDPHP), Centers for Disease Control and Prevention (CDC).
Background and Brief Description
Accounting for an estimated 22,220 cases and 16,210 deaths in 2005,
ovarian cancer is the most frequent cause of death from gynecologic
malignancy in the United States. In over 80 percent of patients,
ovarian cancer presents at a late clinical stage, affording a five-year
survival rate of only 28 percent. For cases where ovarian cancer is
identified in Stage I, however, the five-year survival rate exceeds 90
percent.
Identifying a woman's risk of ovarian cancer plays a large role in
determining the appropriateness of having her undergo screening. It is
only for women with a strong family history of ovarian and/or breast
cancer or women with a
[[Page 17554]]
hereditary genetic risk for ovarian cancer that the currently available
screening modalities of CA 125 and transvaginal ultrasound are
recommended.
Statements from the scientific and medical community regarding
recommendations for ovarian cancer screening play only a partial role
in a woman's decision to undergo screening exams. Numerous
psychological and sociological factors can affect this decision as
well, including a woman's knowledge, attitudes, beliefs, and
experiences. For instance, a woman's experience of cancer within her
family or experience with a friend who has had cancer may influence a
woman's screening decisions.
The literature also notes that women with a family history of
ovarian cancer report increased worry and high levels of perceived
risk. A positive association has also been shown between screening
behavior and family history. Recent studies indicate, however, that
screening is not occurring in proportion to women's levels of risk.
These findings underscore the need for a better understanding of how
perceived risk of ovarian cancer may influence worry about cancer and
ultimately screening behavior.
To address these issues, the Division of Cancer Prevention and
Control (DCPC), at the National Center for Chronic Disease Prevention
and Health Promotion, Centers for Disease Control and Prevention, is
conducting a study to examine the effects of family history of cancer,
knowledge about ovarian cancer, worry and/or anxiety, and perceived
risk of cancer on the likelihood of a woman undergoing screening for
ovarian cancer. By also examining other psycho-social factors such as a
woman's closeness to a relative or friend with cancer, coping style,
cancer worry, use of other cancer screening tests, social support, and
provider's recommendations, the study will elucidate the causal pathway
leading from actual risk (as measured by family history) through
perceived risk to intent to undergo screening and actual screening
behavior.
The proposed study will consist of two tasks. In Task 1, a baseline
survey will be administered through a computer-assisted telephone
interview (CATI) program. Initially, an estimated 32,000 women will be
screened to determine eligibility, and then approximately 2000 women
will be asked a series of questions over a 35-minute time period.
Questions will cover key variables related to ovarian cancer screening
including coping, anxiety, perceived risk, worry, personal cancer
history, family cancer history, closeness with family or friends who
have had cancer, screening behavior, and knowledge of ovarian cancer.
In Task 2, a follow-up questionnaire will be administered, also
using a CATI program, to approximately 1600 of the women included in
the baseline questionnaire. Each of the women will be contacted one
year after they complete the baseline survey. The researchers
anticipate a 15 percent attrition of the sample between baseline and
follow-up. In the follow-up, women will be asked a series of questions
over a 15-minute time period. The purpose of this data collection
effort is to determine if risk perception has changed and to ask about
screening for ovarian cancer, since the baseline questionnaire was
administered.
All data will be collected over a three-year time period. The total
estimated annualized burden hours are 1,411. There are no costs to the
respondents other than their time.
Estimated Annualized Burden Hours
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No. of Avg. burden
Group Type of respondents No. of responses per per response
respondents respondent (in hours)
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Eligibility Screener.................. Women 30 and older...... 10,667 1 5/60
Baseline Survey....................... Women 30 and older 667 1 35/60
(high, elevated or
average risk of ovarian
cancer).
Follow-Up Survey...................... Women who completed the 533 1 15/60
baseline survey.
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Dated: April 3, 2007.
Joan F. Karr,
Acting Reports Clearance Officer, Centers for Disease Control and
Prevention.
[FR Doc. E7-6583 Filed 4-6-07; 8:45 am]
BILLING CODE 4163-18-P