[Federal Register: November 6, 2008 (Volume 73, Number 216)]
[Notices]
[Page 66047-66048]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr06no08-46]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Agency for Toxic Substances and Disease Registry
[ATSDR-247]
Availability of Draft Toxicological Profiles
AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR),
Department of Health and Human Services (HHS).
ACTION: Notice of availability.
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SUMMARY: The Comprehensive Environmental Response, Compensation, and
Liability Act of 1980 (CERCLA), as amended by the Superfund Amendments
and Reauthorization Act of 1986 (SARA), Section 104(i)(3) [42 U.S.C.
9604(i)(3)], directs the Administrator of ATSDR to prepare
toxicological profiles of priority hazardous substances and to revise
and publish each updated toxicological profile as necessary. This
notice announces the availability of the 22nd set of toxicological
profiles, which consists of four updated drafts prepared by ATSDR for
review and comment. The toxicological profiles for formaldehyde and
perfluoroalkyls are on a modified schedule pending additional review.
DATES: In order to be considered, comments on these draft toxicological
profiles must be received on or before February 26, 2009. Comments
received after the public comment period will be considered at the
discretion of ATSDR based on what is deemed to be in the best interest
of the general public.
ADDRESSES: Requests for printed copies of the draft toxicological
profiles should be sent to the attention of Ms. Olga Dawkins, Division
of Toxicology and Environmental Medicine, Agency for Toxic Substances
and Disease Registry, Mailstop F-32, 1600 Clifton Road, NE., Atlanta,
Georgia 30333. Electronic access to these documents is also available
at the ATSDR Web site: http://www.atsdr.cdc.gov/toxpro2.html.
Comments regarding the draft toxicological profiles should be sent
to the attention of Ms. Nickolette Roney, Division of Toxicology and
Environmental Medicine, Agency for Toxic Substances and Disease
Registry, Mailstop F-32, 1600 Clifton Road, NE., Atlanta, Georgia
30333.
Requests for printed copies of the draft toxicological profiles
must be in writing and must specifically identify the hazardous
substance(s) profile(s) that you wish to receive. ATSDR reserves the
right to provide free of charge only one copy of each profile
requested. In case of extended distribution delays, requestors will be
notified.
Written comments and other data submitted in response to this
notice and the draft toxicological profiles should bear the docket
control number ATSDR-247. Send one copy of all comments and three
copies of all supporting documents to Ms. Roney at the above-stated
address by the end of the comment period. Because all public comments
regarding ATSDR toxicological profiles are available for public
inspection, no confidential information should be submitted in response
to this notice.
FOR FURTHER INFORMATION CONTACT: Ms. Olga Dawkins, Division of
Toxicology and Environmental Medicine, Agency for Toxic Substances and
Disease Registry, Mailstop F-32, 1600 Clifton Road, NE., Atlanta,
Georgia 30333; telephone number (800) 232-4636 or (770) 488-3315.
SUPPLEMENTARY INFORMATION: The Superfund Amendments and Reauthorization
Act (SARA) (Pub. L. 99-499) amends the Comprehensive Environmental
Response, Compensation, and Liability Act (CERCLA or Superfund) (42
U.S.C. 9601 et seq.) by establishing certain responsibilities for ATSDR
and the U.S. Environmental Protection Agency (EPA) with regard to
hazardous substances most commonly found at facilities on the CERCLA
National Priorities List (NPL). As part of these responsibilities, the
ATSDR Administrator must prepare toxicological profiles for substances
included on the priority lists of hazardous substances. These lists
identify 275 hazardous substances that ATSDR and EPA determined pose
the most significant potential threat to human health. The availability
of the revised priority list of 275 hazardous substances was announced
in the Federal Register on March 6, 2008 (73 FR 12178). For prior
versions of the list of substances, see Federal Register notices dated
April 17, 1987 (52 FR 12866); October 20, 1988 (53 FR 41280); October
26, 1989 (54 FR 43619); October 17, 1990 (55 FR 42067); October 17,
1991 (56 FR 52166); October 28, 1992 (57 FR 48801); February 28, 1994
(59 FR 9486); April 29, 1996 (61 FR 18744); November 17, 1997 (62 FR
61332); October 21, 1999 (64 FR 56792); October 25, 2001 (66 FR 54014);
November 7, 2003 (68 FR 63098); and December 7, 2005 (70 FR 72840).
[CERCLA also requires ATSDR ensure the initiation of a research program
to satisfy data needs associated with the substances.] Section
[[Page 66048]]
104(i)(3) of CERCLA [42 U.S.C. 9604(i)(3)] outlines the content of
these profiles. Each profile will include an examination, summary, and
interpretation of available toxicological information and epidemiologic
evaluations. This information and these data are to be used to identify
the levels of significant human exposure for the substance and the
associated health effects. The profiles must also include a
determination of whether adequate information on the health effects of
each substance is available or in the process of development. When
adequate information is not available, ATSDR, in cooperation with the
National Toxicology Program (NTP), is required to ensure the initiation
of research to determine these health effects.
Although key studies for each of the substances were considered
during the profile development process, this Federal Register notice
solicits any additional studies, particularly unpublished data and
ongoing studies, which will be evaluated for possible addition to the
profiles now or in the future.
The following draft toxicological profiles will be made available
to the public on or about October 17, 2008.
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Document/Hazardous substance CAS No.
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1. Cadmium.............................................. 007440-43-9
2. Chromium............................................. 007440-47-3
3. Manganese............................................ 007439-96-5
4. Radon................................................ 010043-92-2
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All profiles issued as ``Drafts for Public Comment'' represent
ATSDR's best efforts to provide important toxicological information on
priority hazardous substances. We are seeking public comments and
additional information which may be used to supplement these profiles.
ATSDR remains committed to providing a public comment period for these
documents as the best means to serve public health and our clients.
Dated: November 3, 2008.
Ken Rose,
Director, Office of Policy, Planning and Evaluation, National Center
for Environmental Health/Agency for Toxic Substances and Disease
Registry.
[FR Doc. E8-26472 Filed 11-5-08; 8:45 am]
BILLING CODE 4163-70-P