[Federal Register: December 2, 2008 (Volume 73, Number 232)]
[Notices]
[Page 73329-73332]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr02de08-78]
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DEPARTMENT OF HEALTH AND HUMAN SERVICES
Agency for Toxic Substances and Disease Registry
[ATSDR-248]
Proposed Substances To Be Evaluated for Set 23 Toxicological
Profiles
AGENCY: Agency for Toxic Substances and Disease Registry (ATSDR),
Department of Health and Human Services (HHS).
ACTION: Request for comments on the proposed substances to be evaluated
for Set 23 toxicological profiles.
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SUMMARY: This notice announces the list of proposed substances that
will be evaluated for CERCLA Set 23 toxicological profile development.
ATSDR's Division of Toxicology and Environmental Medicine is soliciting
public nominations from the list of proposed substances to be evaluated
for toxicological profile development. ATSDR also will consider the
evaluation of any additional substances that may have public health
implications.
DATES: Nominations must be submitted by December 24th, 2008.
ADDRESSES: Nominations may be submitted electronically, by mail, or by
facsimile. Refer to the section Submission of Nominations (below) for
specific addresses and/or the facsimile number.
FOR FURTHER INFORMATION: Contact Commander Jessilynn B. Taylor,
Division of Toxicology and Environmental Medicine, Agency for Toxic
Substances and Disease Registry, Mailstop F-32, 1600 Clifton Road, NE.,
Atlanta, Georgia 30333, telephone (770) 488-3313.
SUPPLEMENTARY INFORMATION: The Superfund Amendments and Reauthorization
Act of 1986 (SARA) [42 U.S.C. 9601 et seq.] amended the Comprehensive
Environmental Response, Compensation, and Liability Act of 1980 (CERCLA
or Superfund) [42 U.S.C. 9601 et seq.] by establishing certain
requirements for ATSDR and the U.S. Environmental Protection Agency
(EPA) with regard to hazardous substances that are most commonly found
at facilities on the CERCLA National Priorities List (NPL). Among these
statutory requirements is a mandate for the Administrator of ATSDR to
prepare toxicological profiles for each substance included on the
Priority List of Hazardous Substances. This list has identified 275
hazardous substances that ATSDR and EPA determined pose the most
significant potential threat to human health. The availability of the
revised list of the 275 priority substances was announced in the
Federal Register on March 6, 2008 (73 FR 12178). For previous versions
of the list of substances, see Federal Register notices dated April 17,
1987 (52 FR 12866); October 20, 1988 (53 FR 41280); October 26, 1989
(54 FR 43619); October 17, 1990 (55 FR 42067); October 17, 1991 (56 FR
52166); October 28, 1992 (57 FR 48801); February 28, 1994 (59 FR 9486);
April 29, 1996 (61 FR 18744; November 17, 1997 (62 FR 61332); October
21, 1999 (64 FR 56792); October 25, 2001 (66 FR 54014); November 7,
2003 (68 FR 63098); and December 7, 2005 (70 FR 70284).
Proposed Substances To Be Evaluated for Set 23 Toxicological Profiles
Each year, ATSDR develops a list of priority substances that will
be evaluated for toxicological profile development. This list was
compiled, on the basis of ATSDR's Priority List of Hazardous
Substances, with consideration of the amount of relevance of newly
published scientific
[[Page 73330]]
literature. The following 80 substances will be evaluated:
----------------------------------------------------------------------------------------------------------------
Name CAS
----------------------------------------------------------------------------------------------------------------
1.............................................. MERCURY..................................... 007439-97-6
METHYLMERCURY............................... 022967-92-6
MERCURIC CHLORIDE........................... 007487-94-7
2.............................................. POLYCHLORINATED BIPHENYLS................... 001336-36-3
AROCLOR 1254................................ 011097-69-1
AROCLOR 1260................................ 011096-82-5
AROCLOR 1248................................ 012672-29-6
AROCLOR 1242................................ 053469-21-9
AROCLOR..................................... 012767-79-2
AROCLOR 1221................................ 011104-28-2
AROCLOR 1016................................ 012674-11-2
AROCLOR 1232................................ 011141-16-5
AROCLOR 1240................................ 071328-89-7
TETRACHLOROBIPHENYL......................... 026914-33-0
3.............................................. POLYCYCLIC AROMATIC HYDROCARBONS............ 130498-29-2
BENZO(A)PYRENE............................. 000050-32-8
BENZO(B)FLUORANTHENE........................ 000205-99-2
DIBENZO(A,H)ANTHRACENE...................... 000053-70-3
BENZO(A)ANTHRACENE.......................... 000056-55-3
BENZO(K)FLUORANTHENE........................ 000207-08-9
BENZOFLUORANTHENE........................... 056832-73-6
FLUORANTHENE................................ 000206-44-0
CHRYSENE.................................... 000218-01-9
ACENAPHTHENE................................ 000083-32-9
INDENO(1,2,3-CD)PYRENE...................... 000193-39-5
BENZOPYRENE................................. 073467-76-2
PHENANTHRENE................................ 000085-01-8
PYRENE...................................... 000129-00-0
FLUORENE.................................... 000086-73-7
ANTHRACENE.................................. 000120-12-7
BENZO(A)FLUORANTHENE........................ 000203-33-8
BENZO(GHI)PERYLENE.......................... 000191-24-2
ACENAPHTHYLENE.............................. 000208-96-8
BENZO(J)FLUORANTHENE........................ 000205-82-3
BENZO(E)PYRENE.............................. 000192-97-2
BENZOPERYLENE............................... 011057-45-7
BENZO(B)ANTHRACENE.......................... 000092-24-0
DIBENZ(A,J)ANTHRACENE....................... 000224-41-9
BENZO(GHI)FLUORANTHENE...................... 000203-12-3
1-METHYLPYRENE.............................. 002381-21-7
4.............................................. CHLOROFORM.................................. 000067-66-3
5.............................................. DDT, P,P'-.................................. 000050-29-3
DDE, P,P'-.................................. 000072-55-9
DDD, P,P'-.................................. 000072-54-8
DDT, O,P'-.................................. 000789-02-6
DDD, O,P'................................... -000053-19-0
DDE, O,P'-.................................. 003424-82-6
6.............................................. TRICHLOROETHYLENE........................... 000079-01-6
7.............................................. DIELDRIN.................................... 000060-57-1
ALDRIN...................................... 000309-00-2
8.............................................. CHLORDANE................................... 000057-74-9
CIS-CHLORDANE............................... 005103-71-9
TRANS-CHLORDANE............................. 005103-74-2
OXYCHLORDANE................................ 027304-13-8
GAMMA-CHLORDENE............................. 056641-38-4
CHLORDANE, TECHNICAL........................ 012789-03-6
ALPHA-CHLORDENE............................. 056534-02-2
NONACHLOR, TRANS-........................... 039765-80-5
NONACHLOR, CIS-............................. 005103-73-1
CHLORDENE................................... 003734-48-3
9.............................................. HEXACHLOROBUTADIENE......................... 000087-68-3
10............................................. COAL TAR CREOSOTE........................... 008001-58-9
COAL TARS................................... 008007-45-2
COAL TAR PITCH.............................. 065996-93-2
11............................................. BENZIDINE................................... 000092-87-5
12............................................. TOXAPHENE................................... 008001-35-2
13............................................. TETRACHLOROETHYLENE......................... 000127-18-4
14............................................. 1,2-DIBROMOETHANE........................... 000106-93-4
15............................................. DISULFOTON.................................. 000298-04-4
16............................................. 3,3'-DICHLOROBENZIDINE...................... 000091-94-1
17............................................. ENDRIN...................................... 000072-20-8
[[Page 73331]]
ENDRIN KETONE............................... 053494-70-5
ENDRIN ALDEHYDE............................. 007421-93-4
18............................................. BERYLLIUM................................... 007440-41-7
19............................................. 1,2-DIBROMO-3-CHLOROPROPANE................. 000096-12-8
DIBROMOCHLOROPROPANE........................ 067708-83-2
20............................................. PENTACHLOROPHENOL........................... 000087-86-5
21............................................. DI-N-BUTYL PHTHALATE........................ 000084-74-2
22............................................. ENDOSULFAN.................................. 000115-29-7
ENDOSULFAN SULFATE.......................... 001031-07-8
ENDOSULFAN, ALPHA........................... 000959-98-8
ENDOSULFAN, BETA............................ 033213-65-9
23............................................. METHOXYCHLOR................................ 000072-43-5
24............................................. METHANE..................................... 000074-82-8
25............................................. TOLUENE..................................... 000108-88-3
26............................................. 2-HEXANONE.................................. 000591-78-6
27............................................. 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN......... 001746-01-6
HEXACHLORODIBENZO-P-DIOXIN.................. 034465-46-8
HEPTACHLORODIBENZO-P-DIOXIN................. 037871-00-4
TETRACHLORODIBENZO-P-DIOXIN................. 041903-57-5
PENTACHLORODIBENZO-P-DIOXIN................. 036088-22-9
1,2,3,4,6,7,8-HEPTACHLORODIBENZO-P-DIOXIN... 035822-46-9
OCTACHLORODIBENZO-P-DIOXIN.................. 003268-87-9
1,2,3,6,7,8-HEXACHLORODIBENZO-P-DIOXIN...... 057653-85-7
1,2,3,4,7,8-HEXACHLORODIBENZO-P-DIOXIN...... 039227-28-6
1,2,3,7,8,9-HEXACHLORODIBENZO-P-DIOXIN...... 019408-74-3
1,2,3,7,8-PENTACHLORODIBENZO-P-DIOXIN....... 040321-76-4
28............................................. DI(2-ETHYLHEXYL)PHTHALATE................... 000117-81-7
29............................................. 1,1-DICHLOROETHENE.......................... 000075-35-4
30............................................. METHYLENE CHLORIDE.......................... 000075-09-2
31............................................. BROMODICHLOROETHANE......................... 000683-53-4
32............................................. 1,2-DICHLOROETHANE.......................... 000107-06-2
33............................................. 2,4,6-TRICHLOROPHENOL....................... 000088-06-2
TETRACHLOROPHENOL.......................... 025167-83-3
2,4-DICHLOROPHENOL.......................... 000120-83-2
2,4,5-TRICHLOROPHENOL....................... 000095-95-4
2-CHLOROPHENOL.............................. 000095-57-8
2,3,4,5-TETRACHLOROPHENOL................... 004901-51-3
2,3,5,6-TETRACHLOROPHENOL................... 000935-95-5
2,3,4,6-TETRACHLOROPHENOL................... 000058-90-2
4-CHLOROPHENOL.............................. 000106-48-9
CHLOROPHENOL................................ 025167-80-0
34............................................. 2,4-DINITROPHENOL........................... 000051-28-5
35............................................. BIS(2-CHLOROETHYL) ETHER.................... 000111-44-4
36............................................. ASBESTOS.................................... 001332-21-4
CHRYSOTILE ASBESTOS......................... 012001-29-5
AMOSITE ASBESTOS............................ 012172-73-5
37............................................. HEXACHLOROBENZENE........................... 000118-74-1
38............................................. 2,4-DINITROTOLUENE.......................... 000121-14-2
DINITROTOLUENE.............................. 025321-14-6
2,6-DINITROTOLUENE.......................... 000606-20-2
39............................................. RADIUM-226.................................. 013982-63-3
RADIUM...................................... 007440-14-4
RADIUM-228.................................. 015262-20-1
RADIUM-224.................................. 013233-32-4
40............................................. ETHION...................................... 000563-12-2
41............................................. THORIUM..................................... 007440-29-1
THORIUM-230................................. 014269-63-7
THORIUM-228................................. 014274-82-9
42............................................. 4,6-DINITRO-O-CRESOL........................ 000534-52-1
42............................................. CHLOROBENZENE............................... 000108-90-7
44............................................. N-NITROSODI-N-PROPYLAMINE................... 000621-64-7
45............................................. 1,2,3-TRICHLOROBENZENE...................... 000087-61-6
46............................................. POLONIUM-210................................ 013981-52-7
47............................................. CHLORPYRIFOS................................ 002921-88-2
48............................................. NEPTUNIUM-237............................... 013994-20-2
49............................................. CHLORDECONE................................. 000143-50-0
MIREX....................................... 002385-85-5
50............................................. S,S,S-TRIBUTYL PHOSPHOROTRITHIOATE.......... 000078-48-8
51............................................. BROMINE..................................... 007726-95-6
52............................................. DICOFOL..................................... 000115-32-2
53............................................. PARATHION................................... 000056-38-2
54............................................. SELENIUM.................................... 007782-49-2
55............................................. TRICHLOROFLUOROETHANE....................... 027154-33-2
56............................................. TRIFLURALIN................................. 001582-09-8
[[Page 73332]]
57............................................. 4,4'-METHYLENEBIS(2-CHLOROANILINE).......... 000101-14-4
58............................................. PENTACHLOROBENZENE.......................... 000608-93-5
59............................................. 1,3-BUTADIENE............................... 000106-99-0
60............................................. 1,1-DICHLOROETHANE.......................... 000075-34-3
61............................................. 1,2,3,4,6,7,8,9-OCTACHLORODIBENZOFURAN...... 039001-02-0
HEPTACHLORODIBENZOFURAN..................... 038998-75-3
2,3,4,7,8-PENTACHLORODIBENZOFURAN........... 057117-31-4
HEXACHLORODIBENZOFURAN...................... 055684-94-1
PENTACHLORODIBENZOFURAN..................... 030402-15-4
2,3,7,8-TETRACHLORODIBENZOFURAN............. 051207-31-9
DIBENZOFURANS, CHLORINATED.................. 042934-53-2
1,2,3,4,6,7,8-HEPTACHLORODIBENZOFURAN....... 067562-39-4
1,2,3,7,8,9-HEXACHLORODIBENZOFURAN.......... 072918-21-9
TETRACHLORODIBENZOFURAN..................... 030402-14-3
1,2,3,6,7,8-HEXACHLORODIBENZOFURAN.......... 057117-44-9
1,2,3,4,7,8-HEXACHLORODIBENZOFURAN.......... 070648-26-9
2,3,4,6,7,8-HEXACHLORODIBENZOFURAN.......... 060851-34-5
1,2,3,7,8-PENTACHLORODIBENZOFURAN........... 057117-41-6
1,2,3,4,7,8,9-HEPTACHLORODIBENZOFURAN....... 055673-89-7
62............................................. 1,1,2-TRICHLOROETHANE....................... 000079-00-5
63............................................. HEXACHLOROCYCLOPENTADIENE................... 000077-47-4
64............................................. 1,2-DIPHENYLHYDRAZINE....................... 000122-66-7
65............................................. 1,2-DICHLOROETHENE, TRANS-.................. 000156-60-5
1,2-DICHLOROETHYLENE........................ 000540-59-0
1,2-DICHLOROETHENE, CIS-.................... 000156-59-2
66............................................. CARBON DISULFIDE............................ 000075-15-0
67............................................. PALLADIUM................................... 007440-05-3
68............................................. CHLOROETHANE................................ 000075-00-3
98............................................. ACETONE..................................... 000067-64-1
70............................................. DIBENZOFURAN................................ 000132-64-9
71............................................. 2,4-DIMETHYLPHENOL.......................... 000105-67-9
72............................................. CARBON MONOXIDE............................. 000630-08-0
73............................................. CHLOROMETHANE............................... 000074-87-3
74............................................. BUTYL BENZYL PHTHALATE...................... 000085-68-7
75............................................. VANADIUM.................................... 007440-62-2
76............................................. N-NITROSODIMETHYLAMINE...................... 000062-75-9
77............................................. 1,2,4-TRICHLOROBENZENE...................... 000120-82-1
78............................................. N-NITROSODIPHENYLAMINE...................... 000086-30-6
79............................................. 2-BUTANONE.................................. 000078-93-3
80............................................. FLUORINE.................................... 007782-41-4
HYDROGEN FLUORIDE........................... 007664-39-3
FLUORIDE ION................................ 016984-48-8
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Submission of Nominations for the Evaluation Set 23 Proposed
Substances: Today's notice also invites voluntary public nominations
for substances not listed in this notice. Nominations are most useful
if they include the full name, title, affiliation, e-mail address and
telephone number of the nominator.
ATSDR will evaluate all data and information associated with
nominated substances and will determine the final list of substances
that will be chosen for toxicological profile development. Substances
will be chosen according to ATSDR's specific guidelines for selection,
found in the Selection Criteria announced in the Federal Register on
May 7th, 1993 (87 FR 27288).
Please submit nominations by one of the following methods:
E-mail jxt1@cdc.gov.
Fax 770.488.4178.
Mail CDR Jessilynn Taylor, 1600 Clifton Rd, NE., MS F32,
Atlanta, GA 30333.
Please ensure that your comments are submitted within the specified
nomination period. Nominations received after the closing date will be
marked as late and may be considered only if time permits.
Dated: November 26, 2008.
Ken Rose,
Director, Office of Policy, Planning, and Evaluation National Center
for Environmental Health/Agency for Toxic Substances and Disease
Registry.
[FR Doc. E8-28551 Filed 12-1-08; 8:45 am]
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