[Federal Register: October 2, 2009 (Volume 74, Number 190)]
[Notices]               
[Page 50979-50980]
From the Federal Register Online via GPO Access [wais.access.gpo.gov]
[DOCID:fr02oc09-51]                         

-----------------------------------------------------------------------

DEPARTMENT OF HEALTH AND HUMAN SERVICES

National Institutes of Health

 
National Toxicology Program (NTP); Office of Liaison, Policy and 
Review; Meeting of the NTP Board of Scientific Counselors Technical 
Reports Review Subcommittee

AGENCY: National Institute of Environmental Health Sciences (NIEHS), 
National Institutes of Health (NIH).

ACTION: Meeting announcement and request for comments.

-----------------------------------------------------------------------

SUMMARY: Pursuant to Public Law 92-463, notice is hereby given of a 
meeting of the NTP Board of Scientific Counselors (BSC) Technical 
Reports Review Subcommittee (TRR Subcommittee). The primary agenda 
topic is the peer review of the findings and conclusions presented in 
six draft NTP Technical Reports of rodent toxicology and 
carcinogenicity studies in conventional rats and mice. The TRR 
Subcommittee meeting is open to the public with time scheduled for oral 
public comment. The NTP also invites written comments on the draft 
reports (see ``Request for Comments'' below). The TRR Subcommittee 
deliberations on the draft reports will be reported to the NTP BSC at a 
future meeting.

DATES: The TRR Subcommittee meeting will be held on November 19, 2009. 
All individuals who plan to attend are encouraged to register online by 
November 12, 2009, at the NTP Web site (http://ntp.niehs.nih.gov/go/
15833). The draft reports should be posted by COB October 13, 2009. 
Written comments on the draft reports should be received by November 5, 
2009. Persons needing interpreting services in order to attend should 
contact 301-402-8180 (voice) or 301-435-1908 (TTY). For other 
accommodations while on the NIEHS campus, contact 919-541-2475 or e-
mail niehsoeeo@niehs.nih.gov. Requests should be made at least 7 days 
in advance of the event.

ADDRESSES: The TRR Subcommittee meeting will be held in the Rodbell 
Auditorium, Rall Building at the NIEHS, 111 T. W. Alexander Drive, 
Research Triangle Park, NC 27709. Public comments and any other 
correspondence should be submitted to Dr. Barbara Shane, Executive 
Secretary for the NTP BSC (NTP Office of Liaison, Policy and Review, 
NIEHS, P.O. Box 12233, MD K2-03, Research Triangle Park, NC 27709; 
courier address: Room 2138, 530 Davis Drive, Morrisville, NC 27560; 
telephone: 919-541-4253, fax: 919-541-0295; or e-mail: 
shane@niehs.nih.gov).

SUPPLEMENTARY INFORMATION: 

Background

    The primary agenda topic is the peer review of the findings and 
conclusions of six draft NTP Technical Reports of rodent toxicology and 
carcinogenicity studies (see ``PRELIMINARY AGENDA'' below).

Attendance and Registration

    The meeting is scheduled for November 19, 2009, from 8:30 a.m. to 
adjournment and is open to the public with attendance limited only by 
the space available. Individuals who plan to attend are encouraged to 
register online at the NTP Web site (http://ntp.niehs.nih.gov/go/15833) 
by November 12, 2009, to facilitate access to the NIEHS campus. A photo 
ID is required to access the NIEHS campus. The NTP is making plans to 
videocast the meeting through the Internet at http://www.niehs.nih.gov/
news/video/live.

Availability of Meeting Materials

    A copy of the preliminary agenda, committee roster, and any 
additional information, when available, will be posted on the NTP Web 
site (http://ntp.niehs.nih.gov/go/15833) or may be requested in 
hardcopy from the Executive Secretary (see ADDRESSES above). The draft 
reports should be posted on the NTP Web site by October 13, 2009. 
Following the meeting, summary minutes will be prepared and made 
available on the NTP Web site.

Request for Comments

    The NTP invites written comments on the draft reports, which should 
be received by November 5, 2009, to enable review by the TRR 
Subcommittee and NTP staff prior to the meeting. Persons submitting 
written comments should include their name, affiliation, mailing 
address, phone, e-mail, and sponsoring organization (if any) with the 
document. Written comments received in response to this notice will be 
posted on the NTP Web site, and the submitter will be identified by 
name, affiliation, and/or sponsoring organization.
    Public input at this meeting is also invited and time is set aside 
for the presentation of oral comments on the draft reports. Each 
organization is allowed one time slot per draft report. At least 7 
minutes will be allotted to each speaker, and if time permits, may be 
extended to 10 minutes at the discretion of the chair. Persons wishing 
to make an oral presentation are asked to notify Dr. Barbara Shane via 
online registration at http://ntp.niehs.nih.gov/go/15833, phone, or e-
mail (see ADDRESSES above) by November 12, 2009, and if possible, to 
send a copy of the statement or talking points at that time. Written 
statements can supplement and may expand the oral presentation. 
Registration for oral comments will also be available at the meeting, 
although time allowed for presentation by on-site registrants may be 
less than that for pre-registered speakers and will be determined by 
the number of persons who register on-site.

Background Information on the NTP Board of Scientific Counselors

    The BSC is a technical advisory body comprised of scientists from 
the public and private sectors who provide primary scientific oversight 
to the NTP. Specifically, the BSC advises the NTP on matters of 
scientific program content, both present and future, and conducts 
periodic review of the program for the purposes of determining and 
advising on the scientific merit of its activities and their overall 
scientific quality. The TRR Subcommittee is a standing subcommittee of 
the BSC. BSC members are selected from recognized authorities 
knowledgeable in fields such as toxicology, pharmacology, pathology, 
biochemistry, epidemiology, risk assessment, carcinogenesis, 
mutagenesis, molecular biology, behavioral toxicology and 
neurotoxicology, immunotoxicology, reproductive toxicology or 
teratology, and biostatistics. Its members are invited to serve 
overlapping terms of up to four years. BSC and TRR Subcommittee 
meetings are held annually or biannually.

    Dated: September 23, 2009.
John R. Bucher,
Associate Director, National Toxicology Program.

Preliminary Agenda

NTP Board of Scientific Counselors

Technical Reports Review Subcommittee Meeting

[[Page 50980]]

November 19, 2009

National Institute of Environmental Health Sciences

Rodbell Auditorium, Rall Building

111 T.W. Alexander Drive, Research Triangle Park, NC

Technical Reports (TR) Scheduled for Review

 TR 564 1-Bromopropane (CASRN 106-94-5)
    [cir] Previously used as an intermediate in the production of 
pesticides, quaternary ammonium compounds, flavors, and fragrances. 
Introduced as a less toxic replacement for methylene chloride in 
emissive applications such as vapor and immersion degreasing operations 
and critical cleaning of electronics and metals. Used as a relatively 
nonflammable, nontoxic, fast-drying, and inexpensive solvent for 
adhesive resins, and as a replacement for ozone-depleting refrigerants.
 TR 565 Milk Thistle Extract (CASRN 84604-20-6)
    [cir] Milk thistle extracts are used as herbal medicines to treat a 
variety of diseases (e.g., liver disease) and as a food additive.
 TR 566 Diethylamine (CASRN 109-89-7)
    [cir] Used mainly as a chemical intermediate to produce the 
corrosion inhibitor, N,N-diethylethanolamine, and to lesser extent to 
produce pesticides, insect repellants, pharmaceuticals, and rubber 
processing chemicals.
 TR 567 Ginseng (CASRN 50647-08-0)
    [cir] Ginseng is a perennial aromatic herb widely used in herbal 
remedies for enhancing stamina and endurance for mental and physical 
performance.
 TR 563 Pulegone (CASRN 89-82-7)
    [cir] Several essential oils that contain pulegone are used for 
flavoring foods, drinks, and dental products, as fragrance agents, and 
in herbal medicines.
 TR 536 Bis(2-chloroethoxy) methane (CASRN 111-91-1)
    [cir] Used as a solvent and as the starting agent in the production 
of fungicides and polysulfide polymers.

[FR Doc. E9-23781 Filed 10-1-09; 8:45 am]

BILLING CODE 4140-01-P