[Federal Register Volume 75, Number 105 (Wednesday, June 2, 2010)]
[Notices]
[Page 30779]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2010-13200]
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DEPARTMENT OF COMMERCE
National Institute of Standards and Technology
Notice of Jointly Owned Invention Available for Licensing
AGENCY: National Institute of Standards and Technology, Commerce.
ACTION: Notice of jointly owned invention available for licensing.
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SUMMARY: The invention listed below is jointly owned by the U.S.
Government, as represented by the Department of Commerce, and by
Applied Research Associates, Inc. The Department of Commerce's interest
in the invention is available for licensing in accordance with 35
U.S.C. 207 and 37 CFR part 404 to achieve expeditious commercialization
of results of federally funded research and development.
FOR FURTHER INFORMATION CONTACT: Technical and licensing information on
this invention may be obtained by writing to: National Institute of
Standards and Technology, Office of Technology Partnerships, Building
222, Room A242, Gaithersburg, MD 20899. Information is also available
via telephone: 301-975-2649, fax 301-975-3482, or e-mail:
[email protected]. Any request for information should include the
NIST Docket number or Patent number and title for the invention as
indicated below.
The invention available for licensing is:
[NIST DOCKET NUMBER: 10-004]
Title: Gradient Elution Moving Boundary Electrophoresis for the
Analysis of Complex Samples and Detection of Toxins.
Abstract: Methods of detecting the presence of toxins in a sample
using electrophoretic separations and of performing electrophoretic
separation of complex samples are provided. The method of detecting the
presence of toxins includes reacting a sample and a substrate with a
signaling enzyme which converts the substrate to the product in a
reaction medium, introducing a run buffer into a separation channel
having an inlet end, selectively introducing at least one of the
substrate and the product of the reaction medium into the inlet end of
the separation channel, electrophoretically separating the substrate
and the product, and determining the rate of conversion of the
substrate to the product, wherein a change in the rate of conversion is
indicative of the presence of toxins. The method of performing
electrophoretic separations of complex samples having charged
particulates and oppositely charged analytes comprises introducing a
run buffer into a separation channel having an inlet end, selectively
introducing the oppositely charged analytes in the complex sample into
the separation channel, and electrophoretically separating the charged
particulates and the oppositely charged analytes. Additionally, a
device for varying with respect to time the bulk flow of a fluid in a
separation channel of an electrophoretic device having a buffer
reservoir in fluid contact with the separation channel is provided. The
device includes a pressure sensor in fluid contact with a buffer
reservoir, a high pressure reservoir in selective fluidic communication
with the buffer reservoir, a low pressure reservoir in selective
fluidic communication with the buffer reservoir and in fluidic
communication with the high pressure reservoir, and a pumping device
for pumping a gas from the low pressure reservoir to the high pressure
reservoir.
Dated: May 25, 2010.
Katharine B. Gebbie,
Director, Physics Laboratory.
[FR Doc. 2010-13200 Filed 6-1-10; 8:45 am]
BILLING CODE 3510-13-P