[Federal Register Volume 75, Number 80 (Tuesday, April 27, 2010)]
[Notices]
[Pages 22118-22119]
From the Federal Register Online via the Government Publishing Office [www.gpo.gov]
[FR Doc No: 2010-9747]


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DEPARTMENT OF COMMERCE

National Institute of Standards and Technology


Notice of Invention Available for Licensing

AGENCY: National Institute of Standards and Technology, Commerce.

ACTION: Notice of invention available for licensing.

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SUMMARY: The invention listed below is owned by the U.S. Government, as 
represented by the Department of Commerce. The Department of Commerce's 
interest in the invention is available for licensing in accordance with 
35 U.S.C. 207 and 37 CFR part 404 to achieve expeditious 
commercialization of results of federally funded research and 
development.

FOR FURTHER INFORMATION CONTACT: Technical and licensing information on 
this invention may be obtained by writing to: National Institute of 
Standards and Technology, Office of Technology Partnerships, Building 
222, Room A242, Gaithersburg, MD 20899. Information is also available 
via telephone: 301-975-2649, fax 301-975-3482, or e-mail: 
[email protected]. Any request for information should include the 
NIST Docket number or Patent number and title for the invention as 
indicated below. The invention available for licensing is:

[NIST Docket Number: 06-011CIP]

    Title: Gradient Elution Electrophoresis and Detectorless 
Electrophoresis Apparatus.
    Abstract: A microfluidic apparatus and method for performing 
electrophoretic separation of compounds. The apparatus comprises: (a) A 
first container for containing a sample fluid; (b) a second container 
for containing a separation buffer fluid; (c) a channel of a first 
length having an inlet end and an outlet end, the inlet end connected 
to the first container and the outlet end connected to the second 
container; (d) a voltage device electrically connected to the first 
container and the second container, the voltage device facilitating 
adjustment of the amount of voltage to the first container and the 
second container; (e) a controller for controlling the velocity flow of 
the sample fluid through the channel from the first container towards 
the second container; and (f) a measuring device for measuring the 
current through the channel. The method comprises the steps of: (a) 
Providing a separation buffer; (b) providing a sample solution in fluid 
contact with the separation buffer; (c)

[[Page 22119]]

applying an electric field to the separation buffer; and (d) producing 
a variable bulk flow of the separation buffer in a direction 
substantially aligned with said electric field. Fluid contact between 
the separation buffer and the sample solution is made through a 
separation column having a length in the range of from approximately 
.01 mm to approximately 5 mm. By the foregoing, compounds can be 
sequentially detected and quantified.

    Dated: April 21, 2010.
Marc G. Stanley,
Acting Deputy Director.
[FR Doc. 2010-9747 Filed 4-26-10; 8:45 am]
BILLING CODE 3510-13-P