[Code of Federal Regulations]
[Title 21, Volume 1]
[Revised as of April 1, 2001]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR5.20]

[Page 32-33]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                                SERVICES
 
PART 5--DELEGATIONS OF AUTHORITY AND ORGANIZATION--Table of Contents
 
Subpart B--Redelegations of Authority from the Commissioner of Food and 
                                  Drugs
 
Sec. 5.20  General redelegations of authority from the Commissioner to other officers of the Food and Drug Administration.


    (a) Final authority of the Commissioner of Food and Drugs is 
redelegated as set forth in this subpart.
    (b) The following officials are authorized to perform all of the 
functions of the Commissioner of Food and Drugs and this authority may 
not be further redelegated:
    (1) Deputy Commissioner;
    (2) Associate Commissioner for Regulatory Affairs;
    (3) Senior Associate Commissioner;
    (4) Deputy Commissioner for Management and Systems;
    (5) Senior Associate Commissioner for Policy, Planning, and 
Legislation; and
    (6) Deputy Commissioner for International and Constituent Relations.
    (c)(1) During the absence or disability of the Commissioner, or in 
the event of a vacancy in that position, the first official who is 
available in the following positions, or who has been designated by the 
Commissioner to act in such position, shall act as Commissioner:
    (i) Deputy Commissioner;
    (ii) Associate Commissioner for Regulatory Affairs; or
    (iii) Senior Associate Commissioner.
    (2) This authority may not be further redelegated. However, for a 
planned period of absence, the Commissioner of Food and Drugs (or 
someone ``acting'' on his/her behalf) may specify a different order of 
succession.
    (d) Authority delegated to a position by title may be exercised by a 
person officially designated to serve in that position in an acting 
capacity or on a temporary basis, unless prohibited by a restriction in 
the document designating him as ``acting'' or unless not legally 
permissible.
    (e)(1) The Senior Associate Commissioner is authorized to make 
determinations that advisory committee meetings are concerned with 
matters listed in 5 U.S.C. 552(b) and therefore may be closed to the 
public in accordance with Sec. 5.10(a)(18). This authority may not be 
further redelegated.
    (2) The Senior Associate Commissioner is authorized to perform other 
associated advisory committee functions (e.g., establishing technical 
and scientific review groups (advisory committees)); appointing and 
paying members; approving waivers to appoint members to established 
advisory committees; renewing and rechartering of established advisory 
committees; amending charters of established advisory committees; and 
terminating established advisory committees. This authority may not be 
further redelegated.
    (3) The Senior Associate Commissioner is authorized to approve 
conflict of interest waivers for special Government employees serving on 
advisory committees in accordance with 18 U.S.C. 208(b)(3), as amended. 
This authority may not be further redelegated.
    (4) The Senior Associate Commissioner is authorized to select 
temporary members to advisory committees if such voting members are 
serving on an advisory committee managed by another center. This 
authority may not be further redelegated.
    (f)(1) The Senior Associate Commissioner for Policy, Planning, and 
Legislation and the Associate Commissioner for Policy are authorized to 
perform any of the functions of the Commissioner of Food and Drugs with 
respect to the issuance of Federal Register notices and proposed and 
final regulations of the Food and Drug Administration. This authority 
may not be further redelegated.
    (2) The Senior Associate Commissioner for Policy, Planning, and 
Legislation and the Associate Commissioner for Policy are authorized to 
issue responses to the following matters under part 10 of this chapter 
as follows, and this authority may not be further redelegated:
    (i) Requests for waiver, suspension, or modification of procedural 
requirements under Sec. 10.19 of this chapter;

[[Page 33]]

    (ii) Citizen petitions under Sec. 10.30 of this chapter;
    (iii) Petitions for reconsideration under Sec. 10.33 of this 
chapter;
    (iv) Petitions for stay under Sec. 10.35 of this chapter; or
    (v) Requests for advisory opinions under Sec. 10.85 of this chapter.
    (3) With respect to any matter delegated to the Senior Associate 
Commissioner for Policy, Planning, and Legislation and the Associate 
Commissioner for Policy under paragraph (f) of this section, the Senior 
Associate Commissioner for Policy, Planning, and Legislation and the 
Associate Commissioner for Policy are authorized to perform the function 
of the Commissioner of Food and Drugs under Secs. 10.40, 10.45, 10.50, 
10.55, 10.60, 10.65, 10.80, 10.90, and 10.95 of this chapter and of the 
Deputy Commissioner under Sec. 10.206(g) and (h) of this chapter. This 
authority may not be further redelegated.
    (4) The Senior Associate Commissioner for Policy, Planning, and 
Legislation and the Associate Commissioner for Policy are authorized 
under the Regulatory Flexibility Act (5 U.S.C. 605(b)) to certify that a 
proposed or final rule, if issued, will not have a significant economic 
impact on a substantial number of small entities. This authority may be 
further redelegated.
    (g) The following officials are authorized to perform all of the 
functions of the officials under them in their respective offices, and 
this authority may not be further redelegated:
    (1) Senior Associate Commissioner;
    (2) Deputy Commissioner for International and Constituent Relations;
    (3) Deputy Commissioner for Management and Systems; or
    (4) Senior Associate Commissioner for Policy, Planning, and 
Legislation.
    (h)(1) The Chief Mediator and Ombudsman and the Deputy Chief 
Mediator and Ombudsman are authorized to act upon requests for 
reconsideration of any user fee decisions (under 21 U.S.C. 379h(d)) made 
by such officers and the former Deputy User Fee Waiver Officer prior to 
July 1, 1999. This authority may not be further redelegated. (See 
Sec. 5.101 for the user fee-related redelegation to officials within the 
Center for Drug Evaluation and Research.)
    (2) The Deputy Commissioner for Management and Systems and the 
Director, Office of Financial Management are authorized to perform the 
functions of the Commissioner under 21 U.S.C. 379h(d)(1)(C), as amended, 
to waive or reduce prescription drug user fees in situations where he/
she finds that ``the fees will exceed the anticipated present and future 
costs.'' This authority may not be further redelegated.
    (3) The Deputy Commissioner or, in the event of a vacancy in that 
position, the Senior Associate Commissioner, Office of the Commissioner, 
is designated as the User Fee Appeals Officer. The User Fee Appeals 
Officer is authorized to hear and decide user fee waiver appeals. The 
decision of the User Fee Appeals Officer will constitute final agency 
action on such matters. This authority may not be further redelegated.
    (i) The Deputy Commissioner is authorized to perform the due 
diligence determinations and informal hearings functions under 35 U.S.C. 
156(d)(2)(B)(ii), as amended, relative to patent term extensions. This 
authority may not be further redelegated.
    (j) Authority delegated in the following sections of this subpart 
may not be redelegated.

[43 FR 20487, May 12, 1978, as amended at 48 FR 43300, Sept. 23, 1983; 
56 FR 36001, July 30, 1991; 57 FR 12875, Apr. 14, 1992; 58 FR 17095, 
Apr. 1, 1993; 59 FR 14549, Mar. 29, 1994; 61 FR 2414, Jan. 26, 1996; 62 
FR 923, Jan. 7, 1997; 62 FR 48757, Sept. 17, 1997; 63 FR 41960, Aug. 6, 
1998; 64 FR 59618, Nov. 3, 1999; 65 FR 34960, June 1, 2000]