[Code of Federal Regulations] [Title 21, Volume 6] [Revised as of April 1, 2001] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR524.520] [Page 293-294] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES--(Continued) PART 524--OPHTHALMIC AND TOPICAL DOSAGE FORM NEW ANIMAL DRUGS--Table of Contents Sec. 524.520 Cuprimyxin cream. (a) Specifications. The drug contains 0.5 percent cuprimyxin (6- methoxy-1-phenazinol 5, 10-dioxide, cupric complex) in an aqueous cream base. (b) Sponsor. See No. 000004 in Sec. 510.600(c) of this chapter. (c) Conditions of use. (1) Cuprimyxin is a broad spectrum antibacterial and antifungal cream for the topical treatment of superficial infections in [[Page 294]] horses, dogs, and cats caused by bacteria, dermatophytes (Trichophyton spp., Microsporum spp.) and yeast (Candida albicans) affecting skin, hair, and external mucosae. (2) The cream is applied twice daily to affected areas by rubbing into lesions. Treatment should be continued for a few days after clinical recovery to avoid possible relapses. (3) After application to cutaneous areas, a change in color from dark green to pink is due to the liberation of free myxin from its copper complex. (4) If no response is seen within seven days, diagnosis and therapy should be reevaluated. If any adverse local reaction is observed after topical application, discontinue treatment. (5) Federal law restricts this drug to use by or on the order of a licensed veterinarian. [40 FR 13873, Mar. 27, 1975, as amended at 45 FR 56799, Aug. 26, 1980]