[Code of Federal Regulations]
[Title 21, Volume 6]
[Revised as of April 1, 2001]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR556.344]

[Page 344]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES--(Continued)
 
PART 556--TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD--Table of Contents
 
     Subpart B--Specific Tolerances for Residues of New Animal Drugs
 
Sec. 556.344  Ivermectin.

    (a) Acceptable daily intake (ADI). The ADI for total residues of 
ivermectin is 1 microgram per kilogram of body weight per day.
    (b) Tolerances--(1) Liver. A tolerance is established for 22,23-
dihydroavermectin B1a (marker residue) in liver (target 
tissue) as follows:
    (i) Cattle. 100 parts per billion.
    (ii) Swine. 20 parts per billion.
    (iii) Sheep. 30 parts per billion.
    (iv) Reindeer. 15 parts per billion.
    (v) American bison. 15 parts per billion.
    (2) Muscle. Muscle residues are not indicative of the safety of 
other edible tissues. A tolerance is established for 22,23-
dihydroavermectin B1a (marker residue) in muscle as follows:
    (i) Swine. 20 parts per billion.
    (ii) Cattle. 10 parts per billion.

[63 FR 54352, Oct. 9, 1998, as amended at 64 FR 26671, May 17, 1999]