[Code of Federal Regulations] [Title 21, Volume 6] [Revised as of April 1, 2001] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR558.195] [Page 395-398] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES--(Continued) PART 558--NEW ANIMAL DRUGS FOR USE IN ANIMAL FEEDS--Table of Contents Subpart B--Specific New Animal Drugs for Use in Animal Feeds Sec. 558.195 Decoquinate. (a) Approvals. Type A medicated articles: 6 percent to 046573 in Sec. 510.600(c) of this chapter. (b) Related tolerances in edible products. See Sec. 556.170 of this chapter. (c) Special considerations. (1) Bentonite should not be used in decoquinate feeds. (2) Type A medicated articles containing 6 percent decoquinate may be used to make dry or liquid Type B cattle (including veal calf), sheep, and goat feeds as in paragraph (d) of this section. (3) Type A medicated articles containing 6 percent decoquinate may be used to manufacture dry or liquid Type B cattle feeds as indicated in paragraph (d) of this section. (d) Conditions of use. It is used as follows: ---------------------------------------------------------------------------------------------------------------- Combination in grams Decoquinate in grams per ton per ton Indications for use Limitations Sponsor ---------------------------------------------------------------------------------------------------------------- 13.6 (0.00149 pct).......... ....................... Young goats; for the Feed at a rate to 046573 prevention of provide 22.7 mg per coccidiosis caused by 100 lbs of body Eimeria christenseni weight per day (0.5 and E. mg per kilogram); do ninakohlyakimovae. not feed to goats producing milk for food; feed for at lest 28 days during periods of exposure to coccidiosis or when it is likely to be a hazard. 13.6 (0.0015 pct)........... ....................... Young sheep; for the Feed Type C feed at a 046573 prevention of rate to provide 22.7 coccidiosis caused by mg per 100 lb of body Eimeria ovinoidalis, weight (0.5 mg per E. crandallis, E. kg) per day. Feed at parva, E. bakuensis. least 28 days during periods of exposure to coccidiosis or when it is likely to be a hazard. Do not feed to sheep producing milk for food. [[Page 396]] 13.6 to 27.2 (0.0015 to ....................... Cattle; for the Feed Type C feed at a 0.003 pct). prevention of rate to provide 22.7 coccidiosis in mg per 100 lb of body ruminating and weight (0.5 mg per nonruminating calves kg) per day. May be and cattle caused by prepared from dry or Eimeria bovis and E. liquid Type B feed zumii. containing 0.0125 to 0.5 pct decoquinate. Liquid Type B feed must have a pH range of 5.0 to 6.5 and contain a suspending agent to maintain a viscosity of not less tha 500 centipoises. Feed at least 28 days during periods of exposure to coccidiosis or when it is likely to be a hazard. Do not feed to cows producing milk for food.. Monensin 5 to 30....... Cattle fed in Feed only to cattle 046573 confinement for fed in confinement slaughter; for for slaughter. Feed prevention of continuously as the coccidiosis caused by sole ration to Eimeria bovis and E. provide 22.7 mg of zuernii, and improved decoquinate per 100 feed efficiency.. lb body weight per day and 50 to 360 mg of monensin per head per day. Feed at least 28 days during period of exposure to coccidiosis or when it is likely to be a hazard. Do not feed to animals producing milk for food. Also see (c)(1) of this paragraph and Sec. 558.355(d)(8). Monensin as monensin sodium provided by 000986 in Sec. 510.600(c) of this chapter.. Monensin 5 to 30; plus Cattle fed in Feed only to cattle 046573 tylosin 8 to 10. confinement for fed in confinement slaughter; for for slaughter. Feed prevention of continuously as the coccidiosis caused by sole ration to Eimeria bovis and E. provide 22.7 mg of zuernii, improved decoquinate per 100 feed efficiency, and lb body weight per reduction of day, 50 to 360 mg of incidence of liver monensin per head per abscesses caused by day, and 60 to 90 mg Fusobacterium of tylosin per head necrophorum and per day. Feed at Actinomyces pyogenes.. least 28 days during period of exposure to coccidiosis or when it is likely to be a hazard. Do not feed to animals producing milk for food. Also see (c)(1) of this paragraph and Sec. 558.355(d)(8). Monensin as monensin sodium and tylosin as tylosin phosphate provided by 000986 in Sec. 510.600(c) of this chapter.. [[Page 397]] Chlortetracycline Calves, beef and Feed Type C feed to 046573 approximately 400, nonlactating dairy provide 22.7 mg varying with body cattle: prevention of decoquinate and 1 g weight and feed coccidiosis caused by chlortetracycline/100 consumption to provide Eimeria bovis and E. lb body weight (0.5 10 mg/lb of body zuernii, for mg/kg)/day for not weight per day.. treatment of more than 5 days. bacterial enteritis Type C feed may be caused by Escherichia prepared from Type B coli, and for feed containing 535.8 treatment of to 5,440 g/ton bacterial pneumonia decoquinate and 6,700 caused by Pasteurella to 80,000 g/ton multocida organisms chlortetracycline. susceptible to When consumed, feed chlortetracycline.. 22.7 mg decoquinate/ 100 lb body weight/ day for a total of 28 days to prevent coccidiosis. Withdraw 24 hours prior to slaughter. Do not feed to calves to be processed for veal. Do not feed to animals producing milk for food.. 13.6 to 535.7 (0.0015 to ....................... Cattle: prevention of Feed Type C feed 046573 0.059 pct). coccidiosis in (including dry milk ruminating and replacer) to provide nonruminating calves 22.7 mg per 100 lb (including veal body weight (0.5 mg calves) and cattle per kg) per day. May caused by Eimeria be prepared from dry bovis and E. zurnii.. Type B feed containing 0.06 to 0.6 pct decoquinate or liquid Type B feed containing 0.0125 to 0.05 pct decoquinate. The liquid Type B feed must have pH 5.0 to 6.5 and contain a suspending agent to maintain a viscosity of not less than 500 centipoises. Feed at least 28 days during period of exposure to coccidiosis or when it is likely to be a hazard. Do not feed to animals producing milk for food. ..................... Young sheep: ......do.............. ......do prevention of coccidiosis caused by Eimeria ovinoidalis, E. parva, E. bakuensis, E. crandallis.. ..................... Young goats: ......do.............. ......do prevention of coccidiosis caused by Eimeria christenseni, E. ninakohlyakimovae.. 27.2 (0.003 pct)............ ....................... Broiler chickens; for Do not feed to laying 046573 the prevention of chickens. coccidiosis caused by Eimeria tenella, E. necatrix, E. mivati, E. acervulina, E. maxima and E. brunetti. Bacitracin 4 to 50..... Broiler chickens; for Do not feed to laying 046573 the prevention of chickens; feed coccidiosis caused by continuously as sole Eimeria tenella, E. ration; bacitracin necatrix, E. mivati, methylene E. acervulina, E. disalicylate as maxima, and E. provided by 046573 in brunetti, and for Sec. 510.600(c) of increased rate of this chapter.. weight gain and improved feed efficiency.. Bacitracin 10 to 50.... Broiler chickens; for Do not feed to laying 046573 the prevention of chickens; feed as coccidiosis caused by sole ration; as zinc Eimeria tenella, E. bacitracin provided necatrix, E. mivati, by Nos. 046573 and E. acervulina, E. 011716 in sec. maxima, and E. 510.600(c) of this brunetti; for chapter. increased rate of weight gain and improved feed efficiency. [[Page 398]] Bacitracin methylene Broiler chickens; for Feed continuously as 046573 disalicylate 50 and prevention of sole ration. Withdraw roxarsone 22.7-45.4. coccidiosis caused by 5 days before Eimeria tenella, E. slaughter. Do not necatrix, E. mivati, feed to laying E. acervulina, E. chickens. Not for use maxima, E. brunetti; in breeder chickens. as an aid in the Use as sole source of prevention of organic arsenic. necrotic enteritis Poultry should have caused or complicated access to drinking by Clostridium spp. water at all times. or other organisms Drug overdosage or susceptible to lack of drinking bacitracin; for water may result in increased rate of leg weakness or weight gain, improved paralysis. feed efficiency, and Decoquinate, improved pigmentation. bacitracin methylene disalicylate, and roxarsone, as provided by No. 046573 in Sec. 510.600(c) of this chapter. Chlortetracycline 100 Chickens; for the Do not feed to 046573 to 200. prevention of chickens producing coccidiosis caused by eggs for human Eimeria tenella, E. consumption; in low necatrix, E. mivati, calcium feed E. acervulina, E. containing 0.8 pct. maxima, and E. of calcium; feed brunetti; control of continuously 7 to 14 infectious synovitis days. caused by Mycoplasma synoviae susceptible to chlortetracycline. Chlortetracycline 200 Chickens; for the ......do.............. 046573 to 400. prevention of coccidiosis caused by E. tenella, E. necatrix, E. mivati , E. acervulina, E. maxima, and E. brunetti; control of chronic respiratory disease (CRD) and air sac infection caused by M. gallisepticum and E. coli susceptible to chlortetracycline. Roxarsone 45.4 (0.005 Broiler chickens; for Do not feed to laying 046573 pct.). the prevention of chickens; withdraw 5 coccidiosis caused by days before Eimeria tenella, E. slaughter; as sole necatrix, E. mivati, source of organic E. acervulina, E. arsenic. maxima, and E. brunetti; growth promotion and feed efficiency; improving pigmentation. Lincomycin 2........... Broiler chickens; for Do not feed to laying 000009, the prevention of chickens; feed as 046573 coccidiosis caused by sole ration; as Eimeria tenella, E. lincomycin necatrix, E. hydrochloride acervulina, E. monohydrate provided maxima, E. mivati, by No. 000009 in sec. and E. brunetti; for 510.600(c) of this increased rate of chapter. weight gain and improved feed efficiency. Roxarsone 11 to 45 Broiler chickens; for Do not feed to laying 046573 (0.0012-0.005 pct.) the prevention of chickens; withdraw 5 plus Bacitracin 12 to coccidiosis caused by days before 50. Eimeria tenella, E. slaughter; as sole necatrix, E. source of organic acervulina, E. arsenic; as zinc mivati, E. maxima, bacitracin provided and E. brunetti; for by Nos. 011716, increased rate of 046573, and 063238 in weight gain and sec. 510.600(c) of improved feed this chapter; as efficiency. roxarsone provided by No. 046573 in sec. 510.600(c) of this chapter. ---------------------------------------------------------------------------------------------------------------- [40 FR 13959, Mar. 27, 1975] Editorial Note: For Federal Register citations affecting Sec. 558.195, see the List of CFR Sections Affected, which appears in the Finding Aids section of the printed volume and on GPO Access.