[Code of Federal Regulations] [Title 21, Volume 6] [Revised as of April 1, 2001] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR558.248] [Page 401] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES--(Continued) PART 558--NEW ANIMAL DRUGS FOR USE IN ANIMAL FEEDS--Table of Contents Subpart B--Specific New Animal Drugs for Use in Animal Feeds Sec. 558.248 Erythromycin thiocyanate. (a) Approvals. Type A medicated articles: (1) 2.2 percent to 061133 in Sec. 510.600(c) of this chapter for use as in paragraph (d) of this section. (2) 5 and 10 percent to 061133 for use in paragraphs (d)(1)(i) and (ii) of this section. (b) Special considerations. The levels of antibiotic are expressed in terms of erythromycin master standard. One gram of erythromycin thiocyanate is equivalent to 0.925 gram of erythromycin master standard. (c) Related tolerances. See Sec. 556.230 of this chapter. (d) Condition of use. (1) It is used as follows: ---------------------------------------------------------------------------------------------------------------- Erythromycin thiocyanate in Combination in grams grams per ton per ton Indications for use Limitations Sponsor ---------------------------------------------------------------------------------------------------------------- (i) 4.6 to 18.5............. ....................... Chickens; growth ...................... , promotion and feed 061133 efficiency. (ii) 9.25 to 18.5........... ....................... Turkeys; growth For turkeys not over , promotion and feed 12 weeks of age. 061133 efficiency. (iii) 9.25 to 64.75......... ....................... Swine; increase in Starter ration for 061133 weight gain, improved animals up to 35 lb feed efficiency in body weight. starter pigs (9.25 to 64.75) and grower- finishing pigs (9.25). (iv) 18.5................... ....................... Laying chickens; aids ...................... 061133 in increasing egg production. (v) 92.5.................... ....................... 1. Chickens; as an aid Feed for 2 d before 061133 in the prevention of stress and 3 to 6 d chronic respiratory after stress; disease during withdraw 24 h before periods of stress. slaughter. 2. Chickens; as an aid Feed for 7 to 14 d; in the prevention of withdraw 24 h before infectious coryza. slaughter. 3. Turkeys; as an aid Feed for 2 d before in the prevention of stress and 3 to 6 d chronic respiratory after stress. disease during periods of stress. (vi) 185.................... ....................... 1. Chickens; as an aid Feed for 5 to 8 d; do 061133 in the prevention and not use in birds reduction of lesions producing eggs for and in lowering food purposes; severity of chronic withdraw 48 h before respiratory disease. slaughter. 2. Turkeys; as an aid Feed for 5 to 8 d; do 061133 in the prevention and not use in birds reduction of lesions producing eggs for and in lowering food purposes. severity of chronic respiratory disease. ---------------------------------------------------------------------------------------------------------------- (2) In feed for feedlot beef cattle at 37 milligrams per head per day as an aid in stimulating growth and improving feed efficiency. (3) Erythromycin thiocyanate may be used in accordance with the provisions of this section in the combinations provided as follows: (i) Amprolium in accordance with Sec. 558.55. (ii) Amprolium and ethopabate in accordance with Sec. 558.58. (iii) Arsanilic acid in accordance with Sec. 558.62. (iv) Zoalene in accordance with Sec. 558.680. [41 FR 10999, Mar. 15, 1976, as amended at 45 FR 56799, Aug. 26, 1980; 49 FR 31281, Aug. 6, 1984; 51 FR 7397, Mar. 3, 1986; 52 FR 2684, Jan. 26, 1987; 54 FR 12189, Mar. 24, 1989; 66 FR 14074, Mar. 9, 2001]