[Code of Federal Regulations]
[Title 21, Volume 6]
[Revised as of April 1, 2001]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR558.325]

[Page 417-418]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES--(Continued)
 
PART 558--NEW ANIMAL DRUGS FOR USE IN ANIMAL FEEDS--Table of Contents
 
      Subpart B--Specific New Animal Drugs for Use in Animal Feeds
 
Sec. 558.325  Lincomycin.

    (a) Approvals. Type A articles and Type B feeds approved for 
sponsors in Sec. 510.600(c) of this chapter for specific uses as in 
paragraph (c) of this section as follows:
    (1) No. 000009: (i) 4 grams per pound as in paragraphs (c) (1) and 
(3) of this section.
    (ii) 20 grams per pound as in paragraphs (c) (1) through (3) of this 
section.
    (iii) 50 grams per pound as in paragraphs (c) (1) and (2) of this 
section.
    (iv) 10 grams per pound as in paragraphs (c)(1) and (2) (i) through 
(iv) of this section.
    (2)-(4) [Reserved]
    (5) No. 043733 for 8 and 20 grams per pound as in paragraphs (c)(2) 
(i) through (iii) of this section.
    (6)-(12) [Reserved]
    (13) No. 017800 for 2.5 and 8 grams per pound as in paragraphs 
(c)(2) (i) through (iv) of this section.
    (14)-(15) [Reserved]
    (b) Related tolerances in edible products. See Sec. 556.360 of this 
chapter.
    (c) [Reserved]
    (d) Conditions of use--(1) Broilers:
    (i) Amount per ton. 2 to 4 grams.
    (a) Indications for use. For increase in rate of weight gain and 
improved feed efficiency.
    (b) Limitations. As lincomycin hydrochloride monohydrate.
    (ii) Amount per ton. 2 grams.
    (a) Indications for use. For control of necrotic enteritis caused by 
Clostridium spp. or other susceptible organisms.
    (b) Limitations. As lincomycin hydrochloride monohydrate.
    (2) Swine--(i) Amount per ton. 40 grams.
    (a) Indications for use. For control of swine dysentery.

[[Page 418]]

    (b) Limitations. Feed as sole ration; for use in swine on premises 
with a history of swine dysentery but where symptoms have not yet 
occurred; not to be fed to swine that weigh more than 250 pounds.
    (ii) Amount per ton. 100 grams; 40 grams.
    (a) Indications for use. For treatment and control of swine 
dysentery.
    (b) Limitations. Feed 100 grams per ton for 3 weeks or until signs 
of disease disappear, followed by 40 grams per ton; feed as sole ration; 
not to be fed to swine that weigh more than 250 pounds.
    (iii) Amount per ton. 100 grams.
    (a) Indications for use. For treatment of swine dysentery.
    (b) Limitations. Feed as sole ration for 3 weeks or until signs of 
disease disappear; not to be fed to swine that weigh more than 250 
pounds.
    (iv) Amount per ton. 200 grams.
    (a) Indications for use. For reduction in the severity of swine 
mycoplasmal pneumonia caused by Mycoplasma hyopneumoniae.
    (b) Limitations. Feed as sole ration for 21 days; not to be fed to 
swine that weigh more than 250 pounds.
    (v) Amount per ton. 20 grams.
    (a) Indications for use. For increased rate of weight gain in 
growing-finishing swine.
    (b) Limitations. Feed as sole ration; not for use in swine weighing 
over 250 pounds.
    (3) Lincomycin may also be used for broilers in combination with:
    (i) Amprolium, ethopabate, and roxarsone in accordance with 
Secs. 558.58 and 558.530.
    (ii) Amprolium and ethopabate in accordance with Sec. 558.58.
    (iii) Clopidol in accordance with Sec. 558.175.
    (iv) [Reserved]
    (v) Decoquinate in accordance with Sec. 558.195.
    (vi) Zoalene in accordance with Sec. 558.680.
    (vii) Monensin in accordance with Sec. 558.355.
    (viii) Robenidine hydrochloride in accordance with Sec. 558.515.
    (ix) Roxarsone, monensin sodium in accordance with Secs. 558.355 and 
558.530.
    (x) Lasalocid sodium in accordance with Sec. 558.311.
    (xi) Nicarbazin and roxarsone as in Sec. 558.366.
    (xii) Nicarbazin with or without narasin as in Sec. 558.366.
    (xiii) Lasalocid sodium and roxarsone as in Sec. 558.311.
    (xiv) Halofuginone in accordance with Sec. 558.265.
    (xv) Salinomycin with or without roxarsone as in Sec. 558.550.
    (4) Lincomycin may also be used for swine in combination with:
    (i) Pyrantel tartrate as in Sec. 558.485.
    (ii) Fenbendazole as provided in Sec. 558.258.
    (iii) Ivermectin as in Sec. 558.300.

[40 FR 13959, Mar. 27, 1975]

    Editorial Note: For Federal Register citations affecting 
Sec. 558.325, see the List of CFR Sections Affected, which appears in 
the Finding Aids section of the printed volume and on GPO Access.