[Code of Federal Regulations]
[Title 21, Volume 7]
[Revised as of April 1, 2001]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR700.14]

[Page 127-128]
 
                        TITLE 21--FOOD AND DRUGS
 
          DEPARTMENT OF HEALTH AND HUMAN SERVICES--(Continued)
 
PART 700--GENERAL--Table of Contents
 
         Subpart B--Requirements for Specific Cosmetic Products
 
Sec. 700.14  Use of vinyl chloride as an ingredient, including propellant of cosmetic aerosol products.

    (a) Vinyl chloride has been used as an ingredient in cosmetic 
aerosol products including hair sprays. Where such aerosol products are 
used in the confines of a small room, as is often the case, the level of 
vinyl chloride to which the individual may be exposed could be 
significantly in excess of the safe level established in connection with 
occupational exposure. Evidence indicates that vinyl chloride inhalation 
can result in acute toxicity, manifested by dizziness, headache, 
disorientation, and

[[Page 128]]

unconsciousness where inhaled at high concentrations. Studies also 
demonstrate carcinogenic effects in animals as a result of inhalation 
exposure to vinyl chloride. Furthermore, vinyl chloride has recently 
been linked to liver disease, including liver cancer, in workers engaged 
in the polymerization of vinyl chloride. It is the view of the 
Commissioner that vinyl chloride is a deleterious substance which may 
render any cosmetic aerosol product that contains it as an ingredient 
injurious to users. Accordingly, any cosmetic aerosol product containing 
vinyl chloride as an ingredient is deemed to be adulterated under 
section 601(a) of the Federal Food, Drug, and Cosmetic Act.
    (b) Any cosmetic aerosol product containing vinyl chloride as an 
ingredient shipped within the jurisdiction of the Act is subject to 
regulatory action.

[39 FR 30830, Aug. 26, 1974]