[Code of Federal Regulations]
[Title 14, Volume 5, Parts 1200 to end]
[Revised as of January 1, 2001]
From the U.S. Government Printing Office via GPO Access
[CITE: 14CFR1232.104]

[Page 190]
 
                     TITLE 14--AERONAUTICS AND SPACE
 
                          SPACE ADMINISTRATION
 
PART 1232--CARE AND USE OF ANIMALS IN THE CONDUCT OF NASA ACTIVITIES--Table of Contents
 
Sec. 1232.104  Implementation procedures by non-NASA institutions.

    (a) Proposal Information. No animal subjects may be utilized unless 
a proposal justifying and describing their use is submitted to NASA for 
approval. The required proposal information is outlined in the PHS 
Policy (IV.D.1.a.-e.).
    (b) Proposal Approval by the Institutional ACUC. Before a proposal 
for research involving the use of animal subjects will be considered for 
NASA support, the NASA Headquarters Research or Flight Program Manager 
must receive a statement that the research has been reviewed in 
accordance with the PHS Policy (IV.C.) and approved by the appropriate 
ACUC at the participating institution.
    (c) Proposal Approval for Flight Experiments. In addition to the 
institution's ACUC review, activities involving animal subjects to be 
flown on NASA spacecraft will be subject to review and approval by the 
Ames Research Center (ARC) ACUC. The ARC ACUC will submit each 
evaluation report to the ARC Director who will transmit the report with 
his/her recommendation to the Authorized NASA Official, NASA 
Headquarters. Animal activities to be flown onboard NASA manned 
spacecraft may also be subject to review by the Human Research Policy 
and Procedures Committee (HRPPC) at the Johnson Space Center (JSC). 
Animal activities utilizing the facilities of any NASA field 
installation are also subject to approval of that field installation's 
ACUC (Sec. 1232.105(d)).
    (d) Institutions with PHS Assurance on File. The institution, by an 
approved or provisionally acceptable Assurance on file at the NIH Office 
for Protection from Research Risks (OPRR), Department of Health and 
Human Services (HHS), assures NASA that it will comply with the PHS 
Policy. The Assurance file number must be included in the research 
proposal submitted to NASA.
    (e) Institutions with no PHS Assurance on File. Proposals from 
institutions without an approved Assurance on file with the NIH OPRR 
will first be peer-reviewed for scientific merit. If the proposed 
research is deemed worthy of support, NASA will arrange for a special 
Assurance to be negotiated by the Director, Life Sciences Division, NASA 
Headquarters. The arrangements for a special Assurance review by NIH 
should be undertaken in consultation with the NASA representative to the 
Interagency Research Animal Committee (IRAC) and will be handled on a 
case-by-case basis.
    (f) Foreign institutions must comply with the PHS Policy (see 
Section II Of PHS Policy) and this rule before being supported by NASA 
for any activities involving animal subjects.

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