[Code of Federal Regulations]
[Title 21, Volume 1]
[Revised as of April 1, 2002]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR522.775]

[Page 233-234]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 522--IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS--Table of Contents
 
Sec. 522.775  Doxapram hydrochloride injection.

    (a) Specifications. The drug is a sterile aqueous solution 
containing 20 milligrams doxapram hydrochloride per milliliter.
    (b) Sponsor. See No. 000031 in Sec. 510.600(c) of this chapter.
    (c) Conditions of use. (1) Administer to dogs, cats, and horses to 
stimulate respiration during and after general anesthesia; to speed 
awakening and return of reflexes after anesthesia. Administer to neonate 
dogs and cats to initiate respiration following dystocia or caesarean 
section; to stimulate respiration following dystocia or caesarean 
section.
    (2) For intravenous use in dogs and cats at a dose of 2\1/2\ to 5 
milligrams of doxapram hydrochloride per pound of body weight in 
barbiturate anesthesia, 0.5 mg per lb. in gas anesthesia; for 
intravenous use in horses at 0.25 mg per lb. of body weight in 
barbiturate anesthesia, 0.2 mg per lb. in inhalation anesthesia, 0.25 mg 
per lb. with chloral hydrate with or without magnesium sulfate; for 
subcutaneous, sublingual, or umbilical vein administration in neonate 
puppies at a dose rate of 1 to 5 mg; for subcutaneous or sublingual use 
in neonate kittens at 1 to 2 mg. Dosage may be repeated in 15 to 20 
minutes if necessary.

[[Page 234]]

    (3) Federal law restricts this drug to use by or on the order of a 
licensed veterinarian.

[40 FR 17838, Apr. 23, 1975]