[Code of Federal Regulations] [Title 49, Volume 1] [Revised as of October 1, 2002] From the U.S. Government Printing Office via GPO Access [CITE: 49CFR40.93] [Page 605] TITLE 49--TRANSPORTATION SUBTITLE A--OFFICE OF THE SECRETARY OF TRANSPORTATION PART 40--PROCEDURES FOR TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS--Table of Contents Subpart F--Drug Testing Laboratories Sec. 40.93 What criteria do laboratories use to establish that a specimen is dilute or substituted? (a) As a laboratory you must consider the primary specimen to be dilute if the creatinine concentration is less than 20 mg/dL and the specific gravity is less than 1.003, unless the criteria for a substituted specimen are met. (b) As a laboratory you must consider the primary specimen to be substituted if the creatinine concentration is less than or equal to 5 mg/dL and the specific gravity is less than or equal to 1.001 or greater than or equal to 1.020.