[Code of Federal Regulations] [Title 21 Volume 5] [Revised as of April 1, 2003] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR347.10] [Page 266-267] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) PART 347--SKIN PROTECTANT DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE--Table of Contents Subpart A--Astringent Drug Products Sec. 347.10 Astringent active ingredients. The active ingredient of the product consists of any one of the following within the specified concentration established for each ingredient: (a) Aluminum acetate, 0.13 to 0.5 percent (depending on the formulation and concentration of the marketed product, the manufacturer must provide adequate directions so that the resulting solution to be used by the consumer contains 0.13 to 0.5 percent aluminum acetate). [[Page 267]] (b) Aluminum sulfate, 46 to 63 percent (the concentration is based on the anhydrous equivalent). (c) Witch hazel. [58 FR 54462, Oct. 21, 1993, as amended at 59 FR 28768, June 3, 1994]