[Code of Federal Regulations] [Title 21, Volume 6] [Revised as of January 1, 2003] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR520.100b] [Page 106] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) PART 520--ORAL DOSAGE FORM NEW ANIMAL DRUGS--Table of Contents Sec. 520.100b Amprolium drench. (a) Chemical name. 1-(4-Amino-2-n-propyl - 5 - pyrimidinylmethyl) - 2 - picolinium chloride hydrochloride. (b) Sponsor. See No. 050604 in Sec. 510.600(c) of this chapter. (c) Related tolerances. See Sec. 556.50 of this chapter. (d) Conditions of use. It is used for calves as follows: (1) Amount. 9.6 percent solution or 20 percent soluble powder. (i) Indications for use. As an aid in the treatment of coccidiosis caused by Eimeria bovis and E. zurnii. (ii) Limitations. Add 3 fluid ounces of the 9.6 percent solution to 1 pint of water or 3 ounces of the 20 percent soluble powder to each quart of water and with a dose syringe administer 1 fluid ounce of this solution for each 100 pounds of body weight; this will provide a dose of approximately 10 milligrams per kilogram (2.2 pounds) of body weight; administer daily for 5 days; for a satisfactory diagnosis, a microscopic examination of the feces should be done by a veterinarian or diagnostic laboratory before treatment; when treating outbreaks, the drug should be administered promptly after diagnosis is determined; withdraw 24 hours before slaughter. (2) Amount. 9.6 percent solution or 20 percent soluble powder. (i) Indications for use. As an aid in the prevention of coccidiosis caused by Eimeria bovis and E. zurnii. (ii) Limitations. Add 1\1/2\ fluid ounces of the 9.6 percent solution to 1 pint of water or 1\1/2\ ounces of the 20 percent soluble powder to each quart of water and with a dose syringe administer 1 fluid ounce of this solution for each 100 pounds of body weight; this will provide a dose of approximately 5 milligrams per kilogram (2.2 pounds) of body weight; administer daily for 21 days during periods of exposure or when experience indicates that coccidiosis is likely to be a hazard; withdraw 24 hours before slaughter. [40 FR 13838, Mar. 27, 1975, as amended at 62 FR 63270, Nov. 28, 1997]