[Code of Federal Regulations]
[Title 21, Volume 6]
[Revised as of January 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR520.110]

[Page 107]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 520--ORAL DOSAGE FORM NEW ANIMAL DRUGS--Table of Contents
 
Sec.  520.110  Apramycin sulfate soluble powder.

    (a) Specifications. A water soluble powder used to make a medicated 
drinking water containing apramycin sulfate equivalent to 0.375 gram of 
apramycin activity per gallon of drinking water.
    (b) Sponsor. See No. 000986 in Sec.  510.600(c) of this chapter.
    (c) Related tolerances. See Sec.  556.52 of this chapter.
    (d) Conditions of use. (1) In swine for control of porcine 
colibacillosis (weanling pig scours) caused by strains of E. coli 
sensitive to apramycin.
    (2) It is administered for 7 days in drinking water at the rate of 
12.5 milligrams of apramycin per kilogram (5.7 milligrams per pound) of 
body weight per day. Swine will normally consume 1 gallon per day of 
medicated water containing 375 milligrams of apramycin for each 66 
pounds of body weight. Water consumption should be monitored to 
determine that the required amount of apramycin is being consumed. The 
drug concentration should be adjusted according to water consumption 
which varies depending on ambient temperature, humidity, and other 
factors.
    (3) Prepare fresh medicated water daily.
    (4) Do not slaughter treated swine for 28 days following treatment

[47 FR 15771, Apr. 13, 1982, as amended at 49 FR 19642, May 9, 1984; 53 
FR 37753, Sept. 28, 1988]