[Code of Federal Regulations] [Title 21, Volume 6] [Revised as of January 1, 2003] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR522.468] [Page 227-228] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) PART 522--IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS--Table of Contents Sec. 522.468 Colistimethate sodium powder for injection. (a) Specifications. Each vial contains colistimethate sodium equivalent to 10 grams colistin activity and mannitol to be reconstituted with 62.5 milliliters [[Page 228]] sterile saline or sterile water for injection. The resulting solution contains colistimethate sodium equivalent to 133 milligrams per milliliter colistin activity. (b) Sponsor. See 046573 in Sec. 510.600(c) of this chapter. (c) [Reserved] (d) Conditions of use. (1) 1- to 3-day-old chickens. (i) Dosage. 0.2 milligram colistin activity per chicken. (ii) Indications for use. Control of early mortality associated with Escherichia coli organisms susceptible to colistin. (iii) Limitations. For subcutaneous injection in the neck of 1- to 3-day-old chickens. Not for use in laying hens producing eggs for human consumption. Do not use in turkeys. Federal law restricts this drug to use by or on the order of a licensed veterinarian. (2) [Reserved] [63 FR 13123, Mar. 18, 1998]