[Code of Federal Regulations] [Title 21, Volume 6] [Revised as of January 1, 2003] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR558.274] [Page 411-413] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) PART 558--NEW ANIMAL DRUGS FOR USE IN ANIMAL FEEDS--Table of Contents Subpart B--Specific New Animal Drugs for Use in Animal Feeds Sec. 558.274 Hygromycin B. (a) Approvals. (1) Type A medicated articles: 2.4 and 8 grams per pound to 000986 in Sec. 510.600(c) of this chapter for use as in paragraph (c) of this section. (2) 2.4 grams per pound to 043733 in Sec. 510.600(c) of this chapter for use in swine feed as in paragraph (c)(1)(ii) of this section. (3) [Reserved] (4) 0.6 gram per pound to 017790, 043733, and 050639 in Sec. 510.600(c) of this chapter for use in chickens as in paragraph (c)(1)(i) of this section and in swine as in paragraph (c)(1)(ii) of this section. (5)-(6) [Reserved] (7) 2.4 grams per pound to 017519 in Sec. 510.600(c) of this chapter for use in chickens as in paragraph (c)(1)(i) and in swine as in paragraph (c)(1)(ii) of this section. (8) 0.6 and 1.6 grams per pound granted to 046573 in Sec. 510.600(c) of this chapter for use in chickens as in paragraph (c)(1)(i) and in swine as in paragraph (c)(1)(ii) of this section. (b) Related tolerances. See Sec. 556.330 of this chapter. (c) Conditions of use. (1) It may be used as follows: ---------------------------------------------------------------------------------------------------------------- Hygromycin B in grams per Combination in grams ton per ton Indications for use Limitations Sponsor ---------------------------------------------------------------------------------------------------------------- (i) 8 to 12................. ....................... Chickens: control of Withdraw 3 days before 000986, infestation of large slaughter. 017519, roundworms (Ascaris 017790, galli), cecal worms 043733, (Heterakis gallinae), 046573, and capillary worms 050639 (Capillaria obsignata). Bacitracin 100......... Chickens; control of As bacitracin ......... infestation of large methylene roundworms (Ascaris disalicylate or zinc galli), cecal worms bacitracin; withdraw (Heterakis gallinae), 3 days before and capillary worms slaughter. (Capillaria obsignata); treatment of chronic respiratory disease (airsac infection), blue comb (nonspecific infectious enteritis). Bacitracin plus 1. Chickens; control Feed containing not ......... penicillin (100 to 200 of infestation of less than 25% of of combination). large roundworms penicillin plus not (Ascaris galli), less than 50% of cecal worms bacitracin; as (Heterakis gallinae), procaine penicillin and capillary worms plus bacitracin (Capillaria methylene obsignata); treatment disalicylate; of chronic withdraw 3 days respiratory disease before slaughter. (airsac infection), blue comb (nonspecific infectious enteritis). 2. Chickens; control Combination containing ......... of infestation of not less than 50% nor large roundworms more than 75% of (Ascaris galli), bacitracin, except cecal worms that it contains not (Heterakis gallinae), more than 125 g of and capillary worms penicillin; as (Capillaria procaine penicillin obsignata); treatment plus zinc bacitracin; of chronic withdraw 3 days respiratory disease before slaughter. (airsac infection), blue comb (nonspecific infectious enteritis). [[Page 412]] 3. Chickens, control Combination containing ......... of infestation of 50% to 75% large roundworms bacitracin, but not (Ascaris galli), more than 125 g of cecal worms penicillin, as (Heterakis gallinae), procaine penicillin; and capillary worms withdraw 3 days (Capillaria before slaughter.. obsignata); treatment of chronic respiratory disease (airsac infection), blue comb (nonspecific infectious enteritis). Chlortetracycline 100 Chickens; control of Do not feed to ......... to 200. infestation of large chickens producing roundworms (Ascaris eggs for human galli), cecal worms consumption; feed for (Heterakis gallinae), 7 to 14 days; and capillary worms withdraw 3 days (Capillaria before slaughter. obsignata); control of infectious synovitis caused by Mycoplasma synoviae susceptible to chlortetracycline. Chlortetracycline 200 Chickens; control of ......do.............. ......... to 400. infestation of large roundworms (Ascaris galli), cecal worms (H. Gallinae), and capillary worms (Capillaria obsignata); control of chronic respiratory disease (CRD) and air sac infection caused by Mycoplasma gallisepticum and Escherichia coli susceptible to chlortetracycline. Penicillin 100......... Chickens; control of As procaine ......... infestation of large penicillin; withdraw roundworms (Ascaris 3 days before galli), cecal worms slaughter. (Heterakis gallinae), and capillary worms (Capillaria obsignata); treatment of chronic respiratory disease (airsac infection), blue comb (nonspecific infectious enteritis). Tylosin 4 to 50........ Chickens: Control of As tylosin phosphate; 000986 infestations of large withdraw 3 days roundworms (Ascaris before slaughter. galli), cecal worms (Heterakis gallinae,), and capillary worms (Capillaria obsignata); growth promotion and feed efficiency. (ii) 12..................... ....................... Swine: control of Withdraw 15 days 000986, infestation of large before slaughter. 017519, roundworms (Ascaris 017790, suis), nodular worms 043733, (Oesophagostomum 046573, dentatum), and 050639 whipworms (Trichuris suis). Chlortetracycline 400.. Swine; control of Withdraw 15 d before ......... infestation of large slaughter.. roundworms (Ascaris suis), nodular worms (Oesophagostomum dentatum) and whipworms (Trichuris suis); treatment of bacterial enteritis caused by E. coli and Salmonella choleraesuis and bacterial pneumonia caused by P. multocida susceptible to chlortetracycline.. Tylosin 10 to 100...... Swine: Control of As tylosin phosphate; 000986 infestations of large withdraw 15 days roundworms (Ascaris prior to slaughter; suis), nodular worms feed continuously as (Oesophagostomum follows:. dentatum), and Animal wt.(lbs.):..... whipworms (Trichuris Up to 40........20 to suis); growth 100\1\. promotion and feed 41 to 100........20 efficiency. to 40\1\. 101 to market wt........10 to 20\1\. ---------------------------------------------------------------------------------------------------------------- \1\ Amount of Tylosin (g/t). [[Page 413]] (2) Hygromycin B may also be used in combination with: (i) Amprolium in accordance with Sec. 558.55. (ii) Zoalene in accordance with Sec. 558.680. [41 FR 11000, Mar. 15, 1976] Editorial Note: For Federal Register citations affecting Sec. 558.274, see the List of CFR Sections Affected, which appears in the Finding Aids section of the printed volume and on GPO Access.