[Code of Federal Regulations]
[Title 21, Volume 6]
[Revised as of January 1, 2003]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR558.325]

[Page 423-424]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 558--NEW ANIMAL DRUGS FOR USE IN ANIMAL FEEDS--Table of Contents
 
      Subpart B--Specific New Animal Drugs for Use in Animal Feeds
 
Sec.  558.325  Lincomycin.

    (a) Approvals. Type A articles and Type B feeds approved for 
sponsors in Sec.  510.600(c) of this chapter for specific uses as in 
paragraph (d) of this section as follows:
    (1) No. 000009 for 20 and 50 grams per pound.
    (2)-(4) [Reserved]
    (5) No. 043733 for 8 and 20 grams per pound.
    (6)-(12) [Reserved]
    (13) No. 017800 for 2.5 and 8 grams per pound.
    (14)-(15) [Reserved]
    (b) Related tolerances. See Sec.  556.360 of this chapter.
    (c) [Reserved]
    (d) Conditions of use--(1) Chickens. It is used in feed as follows:

------------------------------------------------------------------------
   Lincomycin      Indications for
   grams/ton             use              Limitations          Sponsor
------------------------------------------------------------------------
(i) 2            Broilers: For       As lincomycin               000009
                  control of          hydrochloride
                  necrotic            monohydrate.
                  enteritis caused
                  by Clostridium
                  spp. or other
                  susceptible
                  organisms.
------------------------------------------------------------------------
(ii) 2 to 4      Broilers: For       As lincomycin               000009
                  increased rate of   hydrochloride
                  weight gain and     monohydrate.
                  improved feed
                  efficiency.
------------------------------------------------------------------------

    (2) Swine. It is used in feed as follows:

------------------------------------------------------------------------
   Lincomycin      Indications for
   grams/ton             use              Limitations          Sponsor
------------------------------------------------------------------------
(i) 20           Growing-finishing   Feed as sole ration.        000009
                  swine: For          Not to be fed to
                  increased rate of   swine that weigh
                  weight gain.        more than 250 pounds
                                      (lb).
------------------------------------------------------------------------
(ii) 40          1. For control of   Feed as sole ration;        000009
                  swine dysentery.    for use in swine on        017800
                                      premises with a            043733
                                      history of swine
                                      dysentery but where
                                      symptoms have not
                                      yet occurred, or
                                      following use of
                                      lincomycin at 100
                                      grams (g)/ton for
                                      treatment of swine
                                      dysentery. Not to be
                                      fed to swine that
                                      weigh more than 250
                                      lb.
                 2. For control of   Feed as sole ration,        000009
                  porcine             or following use of
                  proliferative       lincomycin at 100 g/
                  enteropathies       ton for control of
                  (ileitis) caused    porcine
                  by Lawsonia         proliferative
                  intracellularis.    enteropathies
                                      (ileitis). Not to be
                                      fed to swine that
                                      weigh more than 250
                                      lb.
------------------------------------------------------------------------
(iii) 100        1. For treatment    Feed as sole ration         000009
                  of swine            for 3 weeks or until       017800
                  dysentery.          signs of disease           043733
                                      disappear. Not to be
                                      fed to swine that
                                      weigh more than 250
                                      lb.
                 2. For control of   Feed as sole ration         000009
                  porcine             for 3 weeks or until
                  proliferative       signs of disease
                  enteropathies       disappear. Not to be
                  (ileitis) caused    fed to swine that
                  by Lawsonia         weigh more than 250
                  intracellularis.    lb.
------------------------------------------------------------------------
(iv) 200         For reduction in    Feed as sole ration         000009
                  the severity of     for 3 weeks. Not to        017800
                  swine mycoplasmal   be fed to swine that
                  pneumonia caused    weigh more than 250
                  by Mycoplasma       lb.
                  hyopneumoniae.
------------------------------------------------------------------------

    (3) Lincomycin may also be used in combination with:
    (i) Amprolium and ethopabate or amprolium and ethopabate with 
roxarsone in accordance with Sec.  558.58.
    (ii) Clopidol in accordance with Sec.  558.175.
    (iii) Decoquinate in accordance with Sec.  558.195.
    (iv) Fenbendazole as provided in Sec.  558.258.
    (v) Halofuginone in accordance with Sec.  558.265.
    (vi) Ivermectin as in Sec.  558.300.

[[Page 424]]

    (vii) Lasalocid alone or with roxarsone in accordance with Sec.  
558.311.
    (viii) Monensin alone or with roxarsone in accordance with Sec.  
558.355.
    (ix) Nicarbazin alone or with narasin or roxarsone as in Sec.  
558.366.
    (x) Pyrantel as in Sec.  558.485.
    (xi) Robenidine in accordance with Sec.  558.515.
    (xii) Roxarsone in accordance with Sec.  558.530.
    (xiii) Salinomycin with or without roxarsone as in Sec.  558.550.
    (xiv) Zoalene in accordance with Sec.  558.680.

[40 FR 13959, Mar. 27, 1975]

    Editorial Note: For Federal Register citations affecting Sec.  
558.325, see the List of CFR Sections Affected, which appears in the 
Finding Aids section of the printed volume and on GPO Access.