[Code of Federal Regulations] [Title 21, Volume 7] [Revised as of April 1, 2003] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR610.19] [Page 72-73] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) PART 610--GENERAL BIOLOGICAL PRODUCTS STANDARDS--Table of Contents Subpart B--General Provisions Sec. 610.19 Status of specific products; Group A streptococcus. The presence of Group A streptococcus organisms and derivatives of [[Page 73]] Group A streptococcus in Bacterial Vaccines and Bacterial Antigens with ``No U.S. Standard of Potency'' may induce dangerous tissue reactions in humans. Available data demonstrate that they are unsafe as ingredients in products for human use. Group A streptococcus organisms and derivatives of Group A streptococcus are prohibited from Bacterial Vaccines and Bacterial Antigens with ``No U.S. Standard of Potency.'' Any Bacterial Vaccine or Bacterial Antigen with ``No U.S. Standard of Potency'' containing Group A streptococcus organisms or derivatives of Group A streptococcus in interstate commerce is in violation of section 351 of the Public Health Service Act (42 U.S.C. 262). [44 FR 1549, Jan. 5, 1979]