[Code of Federal Regulations] [Title 21, Volume 1] [Revised as of April 1, 2004] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR12.38] [Page 151-152] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES PART 12_FORMAL EVIDENTIARY PUBLIC HEARING--Table of Contents Subpart B_Initiation of Proceedings Sec. 12.38 Effective date of an order. (a) If a person who is subject to a notice of opportunity for hearing under Sec. 12.21(b) does not request a hearing, the Commissioner will-- (1) Publish a final order denying or withdrawing approval of an NDA, [[Page 152]] NADA, device premarket approval application, or biologics license, in whole or in part, or revoking a device product development protocol or notice of completion, or declaring that such a protocol has not been completed, and stating the effective date of the order; and (2) If the order involves withdrawal of approval of an NADA, forthwith revoke, in whole or in part, the applicable regulation, under section 512(i) of the act. (b) If a person who is subject to a notice of opportunity for hearing under Sec. 12.21(b) requests a hearing and others do not, the Commissioner may issue a final order covering all the drug or device products at once or may issue more than one final order covering different drug or device products at different times.