[Code of Federal Regulations]

[Title 14, Volume 5]

[Revised as of January 1, 2006]

From the U.S. Government Printing Office via GPO Access

[CITE: 14CFR1232.104]



[Page 190]

 

                     TITLE 14--AERONAUTICS AND SPACE

 

                          SPACE ADMINISTRATION

 

PART 1232_CARE AND USE OF ANIMALS IN THE CONDUCT OF NASA ACTIVITIES

--Table of Contents

 

Sec. 1232.104  Implementation procedures by non-NASA institutions.



    (a) Proposal Information. No animal subjects may be utilized unless 

a proposal justifying and describing their use is submitted to NASA for 

approval. The required proposal information is outlined in the PHS 

Policy (IV.D.1.a.-e.).

    (b) Proposal Approval by the Institutional ACUC. Before a proposal 

for research involving the use of animal subjects will be considered for 

NASA support, the NASA Headquarters Research or Flight Program Manager 

must receive a statement that the research has been reviewed in 

accordance with the PHS Policy (IV.C.) and approved by the appropriate 

ACUC at the participating institution.

    (c) Proposal Approval for Flight Experiments. In addition to the 

institution's ACUC review, activities involving animal subjects to be 

flown on NASA spacecraft will be subject to review and approval by the 

Ames Research Center (ARC) ACUC. The ARC ACUC will submit each 

evaluation report to the ARC Director who will transmit the report with 

his/her recommendation to the Authorized NASA Official, NASA 

Headquarters. Animal activities to be flown onboard NASA manned 

spacecraft may also be subject to review by the Human Research Policy 

and Procedures Committee (HRPPC) at the Johnson Space Center (JSC). 

Animal activities utilizing the facilities of any NASA field 

installation are also subject to approval of that field installation's 

ACUC (Sec. 1232.105(d)).

    (d) Institutions with PHS Assurance on File. The institution, by an 

approved or provisionally acceptable Assurance on file at the NIH Office 

for Protection from Research Risks (OPRR), Department of Health and 

Human Services (HHS), assures NASA that it will comply with the PHS 

Policy. The Assurance file number must be included in the research 

proposal submitted to NASA.

    (e) Institutions with no PHS Assurance on File. Proposals from 

institutions without an approved Assurance on file with the NIH OPRR 

will first be peer-reviewed for scientific merit. If the proposed 

research is deemed worthy of support, NASA will arrange for a special 

Assurance to be negotiated by the Director, Life Sciences Division, NASA 

Headquarters. The arrangements for a special Assurance review by NIH 

should be undertaken in consultation with the NASA representative to the 

Interagency Research Animal Committee (IRAC) and will be handled on a 

case-by-case basis.

    (f) Foreign institutions must comply with the PHS Policy (see 

Section II Of PHS Policy) and this rule before being supported by NASA 

for any activities involving animal subjects.



[[Page 191]]