[Code of Federal Regulations]

[Title 14, Volume 5]

[Revised as of January 1, 2006]

From the U.S. Government Printing Office via GPO Access

[CITE: 14CFR1232.106]



[Page 193-194]

 

                     TITLE 14--AERONAUTICS AND SPACE

 

                          SPACE ADMINISTRATION

 

PART 1232_CARE AND USE OF ANIMALS IN THE CONDUCT OF NASA ACTIVITIES

--Table of Contents

 

Sec. 1232.106  Management authority and responsibility.



    (a) Authorized NASA Official. The Authorized NASA Official is the 

NASA Administrator's representative and is responsible for all NASA 

activities involving animal subjects. This individual is responsible for 

implementation of the provisions of this rule and for ensuring that 

agency programs involving animal subjects comply fully with all 

applicable laws, regulations, and guidelines.

    (b) Field Installation Director. The Field Installation Director is 

responsible for and has the authority to:

    (1) Sign the field installation's Assurance, making a commitment on 

behalf of the field installation that the requirements of the PHS Policy 

and this rule will be met in all field installation activities involving 

animal subjects;

    (2) Create and oversee the functioning of the field installation 

ACUC;

    (3) Decide and administer sanctions in cases of noncompliance with 

this rule;

    (4) Fulfill the reporting requirements assigned to this individual 

in Sec. 1232.105(h); and

    (5) Sign the annual USDA report.

    (c) NASA Field Installation(s) ACUC Responsibility. Each NASA Field 

Installation ACUC is responsible to its Field Installation Director for 

the activities described in Sec. Sec. 1232.104(c) and 1232.105 (b), 

(c), (d), (e) and (h).

    (d) Research or Flight Program Manager Responsibility. The Research 

or Flight Program Manager is responsible for ascertaining the presence 

of the required PHS Assurance file number for proposals involving animal 

subjects received from non-NASA institutions, and a statement of ACUC 

review and approval of all NASA and non-NASA proposals involving animal 

subjects. No awards for activities involving animal subjects can be made 

without this documentation [see Sec. Sec. 1232.104 (b) and (d) and 

1232.105(b)].

    (e) NASA Veterinarian(s) Responsibility. NASA veterinarian(s) have 

direct or delegated authority and responsibility for activities 

involving animal subjects at their field installation. Such authority 

and responsibilities shall include recommending approval or disapproval 

of procedures involving animal subjects as a member of the ACUC, 

continual monitoring of these activities, surveillance of the health and 

condition of animal subjects, and reporting any observed deviations from 

approved procedures involving animal subjects to the Field Installation 

Director and the ACUC. In the case of deviation from ACUC-approved 

practices or procedures, the veterinarian shall have the authority to 

immediately halt such procedures until they are reviewed and resolved by 

the ACUC. In cases of a conflict concerning animal usage by an 

investigator that cannot be resolved between him/her and the 

veterinarian, the matter may be brought to the attention of the Field 

Installation ACUC for review and recommendation for action as set forth 

in this rule. Whereas the performance of the veterinarian's duties can 

be delegated to other qualified individuals, the ultimate responsibility 

rests with



[[Page 194]]



the veterinarian. This responsibility extends not only to the Animal 

Care Facility (ACF), but also to other locations where animal subjects 

are used.

    Other specific areas of responsibility and authority vested in the 

veterinarian are:

    (1) Entry of personnel into the ACF. The veterinarian has the 

responsibility to develop access procedures to the ACF and submit them 

to the ACUC for approval.

    (2) Personnel Training. The veterinarian will participate in the 

training of personnel in the handling of animal subjects and in specimen 

sampling procedures.

    (3) Animal Training. The veterinarian will monitor all schedules and 

procedures involving the training and acclimation of animal subjects.

    (4) Surgery and Surgical Procedures. The veterinarian will monitor 

all surgical procedures and verify that the principles of the Guide with 

regard to aseptic surgery are employed. Post-surgical recovery 

procedures are included. If necessary, training will be provided by the 

veterinarian to bring procedures conducted by investigators to the level 

of these standards.

    (5) Veterinary Medical and Engineering Procedures. The veterinarian 

will monitor all veterinary medical and engineering procedures performed 

on animal subjects and verify their appropriateness. The veterinarian 

will actively participate in identifying and/or establishing the design 

requirements and adequacy of animal facilities for ground and 

spaceflight-related activities.

    (f) NASA Representative to the Interagency Research Animal Committee 

(IRAC). The NASA representative to the IRAC will obtain information of 

all cases in which an institution's Assurance has been revoked by the 

PHS. The NASA IRAC representative will notify NASA ACUC's, Field 

Installation Directors, the Authorized NASA Official, and all 

Headquarters Research and Flight Program Managers so that they can 

determine which NASA awards involving the use of animal subjects are 

affected and can take appropriate sanctions.