[Code of Federal Regulations] [Title 40, Volume 23] [Revised as of July 1, 2006] From the U.S. Government Printing Office via GPO Access [CITE: 40CFR158.590] [Page 110-111] TITLE 40--PROTECTION OF ENVIRONMENT CHAPTER I--ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PART 158_DATA REQUIREMENTS FOR REGISTRATION--Table of Contents Subpart D_Data Requirement Tables Sec. 158.590 Nontarget insect data requirements. (a) Table. Sections 158.50 and 158.100 through 158.102 describe how to use this table to determine the nontarget insect data requirements and the substance to be tested. [[Page 111]] ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ General use pattern Test substance ------------------------------------------------------------------------------------------------------------------------------------------- Guidelines Kind of data required (b) Notes Terrestrial Aquatic Greenhouse reference ---------------------------------------------------------------------- Forestry Domestic Indoor Data to support Data to support No. Food crop Nonfood Food crop Nonfood Food crop Nonfood outdoor use MP EP ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Nontarget insect testing-- pollinators Honey bee acute contact LD50.. (1) [CR] [CR] [CR] [CR] ......... ......... [CR] [CR] ......... TGAI............ TGAI............ 141-1 Honey bee--toxicity of (1), (2) CR CR CR CR ......... ......... CR CR ......... TEP............. TEP............. 141-2 residues on foliage. Honey bee subacute feeding (3) .......... .......... .......... .......... ......... ......... ......... ......... ......... ................ ................ 141-4 study. Field testing for pollinators. (4) CR CR CR CR ......... ......... CR CR ......... TEP............. TEP............. 141-5 Nontarget insect testing-- aquatic insects Acute toxicity to aquatic (5) .......... .......... .......... .......... ......... ......... ......... ......... ......... ................ ................ 142-1 insects. Aquatic insect life-cycle (5) .......... .......... .......... .......... ......... ......... ......... ......... ......... ................ ................ 142-1 study. Simulated or actual field (5) .......... .......... .......... .......... ......... ......... ......... ......... ......... ................ ................ 142-3 testing for aquatic insects. Nontarget insect testing-- (5) .......... .......... .......... .......... ......... ......... ......... ......... ......... ................ ................ 143-1 predators and parasites. thru 143-3 ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ Key: CR=Conditionally required; [ ]=Brackets (ie, [CR]) indicate data requirements that apply to products for which an experimental use permit is being sought; TGAI=Technical grade of the active ingredient; TEP=Typical end-use product. (b) Notes. The following notes are referenced in column two of the table contained in paragraph (a) of this section. (1) Required only if proposed use will result in honey bee exposure. (2) Required only when formulation contains one or more active ingredients having an acute LD50 of less than 1 microgram/bee. (3) This requirement is reserved pending development of test methodology. (4) May be required under the following conditions: (i) Data from the honey bee subacute feeding study indicate adverse effects on colonies, especially effects other than acute mortality (reproductive, behavioral, etc.). (ii) Data from residual toxicity studies indicate extended residual toxicity. (iii) Data derived from studies with organisms other than bees indicate properties of the pesticide beyond acute toxicity, such as the ability to cause reproductive or chronic effects. (5) This requirement is reserved pending further evaluation to determine what and when data should be required, and to develop appropriate test methods. [49 FR 42881, Oct. 24, 1984. Redesignated at 53 FR 15993, May 4, 1988, and amended at 58 FR 34203, June 23, 1993]