[Code of Federal Regulations]

[Title 42, Volume 1]

[Revised as of October 1, 2006]

From the U.S. Government Printing Office via GPO Access

[CITE: 42CFR50.605]



[Page 150]

 

                         TITLE 42--PUBLIC HEALTH

 

    CHAPTER I--PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN 

                                SERVICES

 

PART 50_POLICIES OF GENERAL APPLICABILITY--Table of Contents

 

  Subpart F_Responsibility of Applicants for Promoting Objectivity in 

                Research for Which PHS Funding Is Sought

 

Sec.  50.605  Management of conflicting interests.



    (a) The designated official(s) must: Review all financial 

disclosures; and determine whether a conflict of interest exists and, if 

so, determine what actions should be taken by the institution to manage, 

reduce or eliminate such conflict of interest. A conflict of interest 

exists when the designated official(s) reasonably determines that a 

Significant Financial Interest could directly and significantly affect 

the design, conduct, or reporting of the PHS-funded research. Examples 

of conditions or restrictions that might be imposed to manage conflicts 

of interest include, but are not limited to:

    (1) Public disclosure of significant financial interests;

    (2) Monitoring of research by independent reviewers;

    (3) Modification of the research plan;

    (4) Disqualification from participation in all or a portion of the 

research funded by the PHS;

    (5) Divestiture of significant financial interests; or

    (6) Severance of relationships that create actual or potential 

conflicts.

    (b) In addition to the types of conflicting financial interests 

described in this paragraph that must be managed, reduced, or 

eliminated, an Institution may require the management of other 

conflicting financial interests, as the Institution deems appropriate.