[Code of Federal Regulations]
[Title 21, Volume 6]
[Revised as of April 1, 2007]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR556.113]

[Page 349]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 556_TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD--Table of 
 
     Subpart B_Specific Tolerances for Residues of New Animal Drugs
 
Sec.  556.113  Ceftiofur.

    (a) Acceptable daily intake and acceptable single-dose intake--(1) 
Acceptable daily intake (ADI). The ADI for total residues of ceftiofur 
is 30 micrograms per kilogram of body weight per day.
    (2) Acceptable single-dose intake (ASDI). The ASDI total residues of 
ceftiofur is 0.830 milligrams per kilogram of body weight. The ASDI is 
the amount of total residues of ceftiofur that may safely be consumed in 
a single meal. The ASDI is used to derive the tolerance for residues of 
desfuroylceftiofur at the injection site.
    (b) Tolerances--(1) Poultry, and sheep. A tolerance for residues of 
ceftiofur in edible tissue is not required.
    (2) Swine. The tolerances for desfuroylceftiofur (marker residue) 
are:
    (i) Kidney (target tissue). 0.25 parts per million (ppm).
    (ii)Liver. 3 ppm.
    (iii) Muscle. 2 ppm.
    (3) Cattle. The tolerances for desfuroylceftiofur (marker residue) 
are:
    (i) Kidney (target tissue). 0.4 ppm.
    (ii) Liver. 2 ppm.
    (iii)Muscle. 1 ppm.
    (iv) Milk. 0.1 ppm.

[63 FR 53579, Oct. 6, 1998, as amended at 68 FR 60296, Oct. 22, 2003; 69 
FR 43892, July 23, 2004; 71 FR 39546, July 13, 2006]