[Code of Federal Regulations]
[Title 21, Volume 1]
[Revised as of April 1, 2007]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR70.11]

[Page 327]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                                SERVICES
 
PART 70_COLOR ADDITIVES--Table of Contents
 
                      Subpart A_General Provisions
 
Sec.  70.11  Related substances.

    (a) Different color additives may cause similar or related 
pharmacological or biological effects, and, in the absence of evidence 
to the contrary, those that do so will be considered to have additive 
toxic effects.
    (b) Food additives may also cause pharmacological or biological 
effects similar or related to such effects caused by color additives, 
and, in the absence of evidence to the contrary, those that do so will 
be considered as having additive toxic effects.
    (c) Pesticide chemicals may also cause pharmacological or biological 
effects similar or related to such effects caused by color additives, 
and, in the absence of evidence to the contrary, those that do so will 
be considered to have additive toxic effects.
    (d) In establishing tolerances for color additives, the Commissioner 
will take into consideration, among other things, the amount of any 
common component permitted in other color additives, in food additives, 
and in pesticide chemical residues as well as the similar biological 
activity (such as cholinesterase inhibition) produced by such substance.