[Code of Federal Regulations] [Title 21, Volume 1] [Revised as of April 1, 2007] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR99.1] [Page 446] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES PART 99_DISSEMINATION OF INFORMATION ON UNAPPROVED/NEW USES FOR MARKETED Subpart A_General Information Sec. 99.1 Scope. (a) This part applies to the dissemination of information on human drugs, including biologics, and devices where the information to be disseminated: (1) Concerns the safety, effectiveness, or benefit of a use that is not included in the approved labeling for a drug or device approved by the Food and Drug Administration for marketing or in the statement of intended use for a device cleared by the Food and Drug Administration for marketing; and (2) Will be disseminated to a health care practitioner, pharmacy benefit manager, health insurance issuer, group health plan, or Federal or State Government agency. (b) This part does not apply to a manufacturer's dissemination of information that responds to a health care practitioner's unsolicited request.