[Code of Federal Regulations] [Title 21, Volume 2] [Revised as of April 1, 2008] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR111.117] [Page 243] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) PART 111_CURRENT GOOD MANUFACTURING PRACTICE IN MANUFACTURING, PACKAGING, LABELING, OR HOLDING OPERATIONS FOR DIETARY SUPPLEMENTS--Table of Contents Subpart F_Production and Process Control System: Requirements for Quality Control Sec. 111.117 What quality control operations are required for equipment, instruments, and controls? Quality control operations for equipment, instruments, and controls must include: (a) Reviewing and approving all processes for calibrating instruments and controls; (b) Periodically reviewing all records for calibration of instruments and controls; (c) Periodically reviewing all records for calibrations, inspections, and checks of automated, mechanical, or electronic equipment; and (d) Reviewing and approving controls to ensure that automated, mechanical, or electronic equipment functions in accordance with its intended use.