[Code of Federal Regulations]
[Title 21, Volume 4]
[Revised as of April 1, 2008]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR225.20]

[Page 164-165]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 225_CURRENT GOOD MANUFACTURING PRACTICE FOR MEDICATED FEEDS--Table of Contents
 
   Subpart B_Construction and Maintenance of Facilities and Equipment
 
Sec.  225.20  Buildings.


    (a) The location, design, construction, and physical size of the 
buildings and other production facilities are factors important to the 
manufacture of medicated feed. The features of facilities necessary for 
the proper manufacture of medicated feed include provision for ease of 
access to structures

[[Page 165]]

and equipment in need of routine maintenance; ease of cleaning of 
equipment and work areas; facilities to promote personnel hygiene; 
structural conditions for control and prevention of vermin and pest 
infestation; adequate space for the orderly receipt and storage of drugs 
and feed ingredients and the controlled flow of these materials through 
the processing and manufacturing operations; and the equipment for the 
accurate packaging and delivery of a medicated feed of specified 
labeling and composition.
    (b) The construction and maintenance of buildings in which medicated 
feeds are manufactured, processed, packaged, labeled, or held shall 
conform to the following:
    (1) The building grounds shall be adequately drained and routinely 
maintained so that they are reasonably free from litter, waste, refuse, 
uncut weeds or grass, standing water, and improperly stored equipment.
    (2) The building(s) shall be maintained in a reasonably clean and 
orderly manner.
    (3) The building(s) shall be of suitable construction to minimize 
access by rodents, birds, insects, and other pests.
    (4) The buildings shall provide adequate space and lighting for the 
proper performance of the following medicated feed manufacturing 
operations:
    (i) The receipt, control, and storage of components.
    (ii) Component processing.
    (iii) Medicated feed manufacturing.
    (iv) Packaging and labeling.
    (v) Storage of containers, packaging materials, labeling and 
finished products.
    (vi) Routine maintenance of equipment.