[Code of Federal Regulations] [Title 21, Volume 5] [Revised as of April 1, 2008] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR347.20] [Page 275-276] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF PART 347_SKIN PROTECTANT DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE--Table of Contents Subpart B_Active Ingredients Sec. 347.20 Permitted combinations of active ingredients. (a) Combinations of skin protectant active ingredients. (1) Any two or more of the ingredients identified in Sec. 347.10(a), (d), (e), (i), (k), (l), (m), and (r) may be combined provided the combination is labeled according to Sec. 347.50(b)(1) and provided each ingredient in the combination is within the concentration specified in Sec. 347.10. (2) Any two or more of the ingredients identified in Sec. 347.10(a), (d), (e), (g), (h), (i), (k), (l), (m), and (r) may be combined provided the combination is labeled according to Sec. 347.50(b)(2) and provided each ingredient in the combination is within the concentration specified in Sec. 347.10. (3) Any two or more of the ingredients identified in Sec. 347.10(b), (c), (j), (s), (t), and (u) may be combined provided the combination is labeled according to Sec. 347.50(b)(3) and provided each ingredient in the combination is within the concentration specified in Sec. 347.10. [[Page 276]] (4) The ingredients identified in Sec. 347.10(f) and (l) may be combined provided the combination is labeled according to Sec. 347.50(b)(7) and provided each ingredient in the combination is within the concentration specified in Sec. 347.10. (b) Combinations of skin protectant and external analgesic active ingredients. Any one (two when required to be in combination) or more of the active ingredients identified in Sec. 347.10(a), (d), (e), (i), (k), (l), (m), and (r) may be combined with any of the following generally recognized as safe and effective external analgesic active ingredients: Single amine and ``caine''-type local anesthetics, alcohols and ketones, antihistamines, or any permitted combination of these ingredients, but not with hydrocortisone, provided the product is labeled according to Sec. 347.60(b)(l). (c) Combinations of skin protectant and first aid antiseptic active ingredients. Any one (two when required to be in combination) or more of the active ingredients identified in Sec. 347.10(a), (d), (e), (i), (k), (l), (m), and (r) may be combined with any generally recognized as safe and effective single first aid antiseptic active ingredient, or any permitted combination of these ingredients, provided the product is labeled according to Sec. 347.60(b)(2). (d) Combinations of skin protectant and sunscreen active ingredients. Any one (two when required to be in combination) or more of the skin protectant active ingredients identified in Sec. 347.10(a), (d), (e), (g), (h), (i), (k), (l), (m), and (r) may be combined with any generally recognized as safe and effective single sunscreen active ingredient, or any permitted combination of these ingredients, provided the product meets the conditions in Sec. 352.20(b) of this chapter and is labeled according to Sec. Sec. 347.60(b)(3) and 352.60(b) of this chapter. Effective Date Note: At 68 FR 33377, June 4, 2003, in Sec. 347.20 paragraph (d) was stayed until further notice, effective June 4, 2004.