[Code of Federal Regulations] [Title 21, Volume 7] [Revised as of April 1, 2008] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR601.32] [Page 38-39] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) PART 601_LICENSING--Table of Contents Subpart D_Diagnostic Radiopharmaceuticals Sec. 601.32 General factors relevant to safety and effectiveness. FDA's determination of the safety and effectiveness of a diagnostic radiopharmaceutical includes consideration of the following: (a) The proposed use of the diagnostic radiopharmaceutical in the practice of medicine; (b) The pharmacological and toxicological activity of the diagnostic radiopharmaceutical (including any [[Page 39]] carrier or ligand component of the diagnostic radiopharmaceutical); and (c) The estimated absorbed radiation dose of the diagnostic radiopharmaceutical.