[Code of Federal Regulations]
[Title 21, Volume 7]
[Revised as of April 1, 2008]
From the U.S. Government Printing Office via GPO Access
[CITE: 21CFR700.14]

[Page 137-138]
 
                        TITLE 21--FOOD AND DRUGS
 
CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN 
                          SERVICES (CONTINUED)
 
PART 700_GENERAL--Table of Contents
 
          Subpart B_Requirements for Specific Cosmetic Products
 
Sec. 700.14  Use of vinyl chloride as an ingredient, including propellant of 

cosmetic aerosol products.

    (a) Vinyl chloride has been used as an ingredient in cosmetic 
aerosol products including hair sprays. Where such aerosol products are 
used in the confines of a small room, as is often the case, the level of 
vinyl chloride to which the

[[Page 138]]

individual may be exposed could be significantly in excess of the safe 
level established in connection with occupational exposure. Evidence 
indicates that vinyl chloride inhalation can result in acute toxicity, 
manifested by dizziness, headache, disorientation, and unconsciousness 
where inhaled at high concentrations. Studies also demonstrate 
carcinogenic effects in animals as a result of inhalation exposure to 
vinyl chloride. Furthermore, vinyl chloride has recently been linked to 
liver disease, including liver cancer, in workers engaged in the 
polymerization of vinyl chloride. It is the view of the Commissioner 
that vinyl chloride is a deleterious substance which may render any 
cosmetic aerosol product that contains it as an ingredient injurious to 
users. Accordingly, any cosmetic aerosol product containing vinyl 
chloride as an ingredient is deemed to be adulterated under section 
601(a) of the Federal Food, Drug, and Cosmetic Act.
    (b) Any cosmetic aerosol product containing vinyl chloride as an 
ingredient shipped within the jurisdiction of the Act is subject to 
regulatory action.

[39 FR 30830, Aug. 26, 1974]