[Code of Federal Regulations] [Title 21, Volume 8] [Revised as of April 1, 2008] From the U.S. Government Printing Office via GPO Access [CITE: 21CFR866.3210] [Page 264-265] TITLE 21--FOOD AND DRUGS CHAPTER I--FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) PART 866_IMMUNOLOGY AND MICROBIOLOGY DEVICES--Table of Contents Subpart D_Serological Reagents Sec. 866.3210 Endotoxin assay. (a) Identification. An endotoxin assay is a device that uses serological techniques in whole blood. The device is intended for use in conjunction with other laboratory findings and clinical assessment of the patient to aid in the risk assessment of critically ill patients for progression to severe sepsis. (b) Classification. Class II (special controls). The special control for this [[Page 265]] device is the FDA guidance entitled ``Class II Special Controls Guidance Document: Endotoxin Assay.'' See Sec. 866.1(e) for the availability of this guidance document. [68 FR 62008, Oct. 31, 2003. Redesignated at 70 FR 53069, Sept. 7, 2005]